GLP-1 receptor analogue

Russian translation: аналог рецептора глюкагоноподобного пептида-1

17:22 Feb 26, 2014
English to Russian translations [PRO]
Medical - Medical: Pharmaceuticals
English term or phrase: GLP-1 receptor analogue
Taking into consideration ХХХХ mode of action, there is not an option in this trial to combine study drug (i.e., placebo or ХХХХ) with a GLP-1 receptor analogue as the DPP4 inhibitor and GLP1receptor analogue combination is not approved or indicated (per label of all GLP-1 products and DPP4 inhibitors).
Anastasia Serdyukova
Russian Federation
Local time: 01:50
Russian translation:аналог рецептора глюкагоноподобного пептида-1
Explanation:
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Note added at 1 час (2014-02-26 18:47:20 GMT)
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http://www.google.com.ua/url?sa=t&rct=j&q=&esrc=s&source=web...

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Note added at 1 час (2014-02-26 19:07:00 GMT)
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..."Liraglutide is a glucagon-like peptide-1 receptor analogue, which is obtained by derivatising glucagon-like peptide-1 with a fatty acid, providing a compound with pharmacokinetic properties that are suitable for once-daily dosing"...

http://www.ncbi.nlm.nih.gov/pubmed/17243943

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Note added at 1 час (2014-02-26 19:15:54 GMT)
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Вот еще интересная цитата:
"Victoza, second GLP-1 receptor analogue
Published on 05/08/09
Вот еще одна интересная ссылка:
Novo Nordisk has introduced liraglutide (Victoza), a new GLP-1 receptor agonist (incretin mimetic) for the treatment of type 2 diabetes".
http://www.prescriber.co.uk/details/news/346145/Victoza_seco...


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Note added at 2 час (2014-02-26 19:23:45 GMT)
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По этой ссылке видно, что лираглутид вначале назвали "агонистом" рецептора, а затем уже "аналогом" рецептора.

Поэтому я думаю, что можно использовать оба термина, хотя "агонист" более привычен для нас.
Selected response from:

Doctor Alex
Local time: 01:50
Grading comment
4 KudoZ points were awarded for this answer



Summary of answers provided
4 +1аналог рецептора глюкагоноподобного пептида-1
Doctor Alex
Summary of reference entries provided
comment
liz askew
glp-1
svetlayk

  

Answers


1 hr   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +1
glp-1 receptor analogue
аналог рецептора глюкагоноподобного пептида-1


Explanation:
.

--------------------------------------------------
Note added at 1 час (2014-02-26 18:47:20 GMT)
--------------------------------------------------

http://www.google.com.ua/url?sa=t&rct=j&q=&esrc=s&source=web...

--------------------------------------------------
Note added at 1 час (2014-02-26 19:07:00 GMT)
--------------------------------------------------

..."Liraglutide is a glucagon-like peptide-1 receptor analogue, which is obtained by derivatising glucagon-like peptide-1 with a fatty acid, providing a compound with pharmacokinetic properties that are suitable for once-daily dosing"...

http://www.ncbi.nlm.nih.gov/pubmed/17243943

--------------------------------------------------
Note added at 1 час (2014-02-26 19:15:54 GMT)
--------------------------------------------------

Вот еще интересная цитата:
"Victoza, second GLP-1 receptor analogue
Published on 05/08/09
Вот еще одна интересная ссылка:
Novo Nordisk has introduced liraglutide (Victoza), a new GLP-1 receptor agonist (incretin mimetic) for the treatment of type 2 diabetes".
http://www.prescriber.co.uk/details/news/346145/Victoza_seco...


--------------------------------------------------
Note added at 2 час (2014-02-26 19:23:45 GMT)
--------------------------------------------------

По этой ссылке видно, что лираглутид вначале назвали "агонистом" рецептора, а затем уже "аналогом" рецептора.

Поэтому я думаю, что можно использовать оба термина, хотя "агонист" более привычен для нас.


Doctor Alex
Local time: 01:50
Specializes in field
Native speaker of: Native in RussianRussian, Native in UkrainianUkrainian
PRO pts in category: 786

Peer comments on this answer (and responses from the answerer)
agree  Natalie: Согласна с тем, что написано в строке ответа, но аналог и агонист - это два совершенно разных свойства
3 hrs
  -> Спасибо.
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Reference comments


30 mins
Reference: comment

Reference information:
purely out of interest I looked up your phrase but was only able to locate

GLP-1 analogue

OR

GLP-1 receptor agonist


1. Incretin Mimetics (GLP-1 Agonists) - Suitability, Benefits & Side Effects
www.diabetes.co.uk › Medication‎
o
o
The drugs, also commonly known as glucagon-like peptide 1 (GLP-1) receptor agonists or GLP-1 analogues, are normally prescribed for patients who have not ...


Practical Diabetes Care - Google Books Result
books.google.co.uk/books?isbn=1444391143
David Levy - 2004 - ‎Health & Fitness
therapeutic effects of GLP-1: - development of GLP-1 analogues/receptor agonists (incretin mimetics) that directly act at the B cell; 0 development of drugs .


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Note added at 35 mins (2014-02-26 17:57:50 GMT)
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I did find this though

GLP–1 receptor agonists and DPP–4 inhibitors - Cleveland Clinic ...
www.ccjm.org/content/76/Suppl_5/S28.full
by JA DAVIDSON - ‎2009 - ‎Cited by 48 - ‎Related articles
Also undergoing regulatory review is the partly DPP-4–resistant acylated GLP-1 receptor agonist liraglutide. 13 Liraglutide, ****a human analogue GLP-1 receptor**** ...

liz askew
United Kingdom
Works in field
Native speaker of: Native in EnglishEnglish
PRO pts in category: 4
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43 mins
Reference: glp-1

Reference information:
http://ru.wikipedia.org/wiki/Глюкагоноподобный_пептид-1

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Note added at 47 mins (2014-02-26 18:10:16 GMT)
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Тот же вопрос возник что и у Лизы. Возможни ли какая либо описка или ошибочка термина, может при переписи со звукового носителя???
А вот ссылка на DPP-4 если полезно будет:
http://ru.wikipedia.org/wiki/DPP4

svetlayk
United Kingdom
Native speaker of: Native in RussianRussian
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