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breakthrough pain

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18:37 Jan 9, 2012

English to English translations [PRO]
Medical - Medical: Pharmaceuticals

English term or phrase: breakthrough pain

Many times patients are prescribed time release medication - which may last 8 to 12 hours. Some patients may have pain which "breaks through" the pain barrier and they need to take a smaller dose of the same or similar medication to relieve the "breakthrough pain"

carol nickerson

English translation:see explanation

Explanation:
pain that is stronger than the pain for which the dose of the drug was prescribed for, i.e. extreme pain that is not completely allayed by the dose of administered medication

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Jonathan MacKerron
Local time: 04:04

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breakthrough pain

Pharma cist

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Jonathan MacKerron

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52 mins confidence:

peer agreement (net): +2

see explanation

Explanation:
pain that is stronger than the pain for which the dose of the drug was prescribed for, i.e. extreme pain that is not completely allayed by the dose of administered medication

Jonathan MacKerron
Local time: 04:04
Specializes in field
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English
PRO pts in category: 20

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1 day20 mins confidence:

breakthrough pain

Explanation:
Currently, there is no universally accepted definition for breakthrough pain.

The original definition of breakthrough pain was “a transitory exacerbation of pain that occurs on a background of otherwise stable pain in a patient receiving chronic opioid therapy” [1].

An updated version of the definition of breakthrough pain is “a transitory exacerbation of pain experienced by the patient who has relatively stable and adequately controlled baseline pain” [2].

Recently, an expert group has suggested an extension of the updated version of the definition of breakthrough pain: “a transient exacerbation of pain that occurs either spontaneously, or in relation to a specific predictable or unpredictable trigger, despite relatively stable and adequately controlled background pain” [3].

References:
1. Portenoy RK, Hagen NA. Breakthrough pain: definition, prevalence and characteristics. Pain 1990; 41(3): 273-81.
2. Portenoy et al. Difficult pain problems: an integrated approach. In: Doyle et al, editors. Oxford Textbook of Palliative Medicine. 3rd ed. Oxford: Oxford University Press; 2004. p. 438-58.
3. Davies et al. The management of cancer-related breakthrough pain: recommendations of a task group of the Science Committee of the Association for Palliative Medicine of Great Britain and Ireland. European Journal of Pain 2009; 13(4): 331-8.

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