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on the primary measure of

English translation: the principal way in which cognition is being assessed


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10:06 Nov 16, 2009
English to English translations [PRO]
Medical - Medical (general) / Alzheimer
English term or phrase: on the primary measure of
To evaluate the efficacy of XYZ as compared to placebo on the primary measure of cognition.
[how to understand the formulation "on the primary measure of ..."?]
jmarcin2
English translation:the principal way in which cognition is being assessed
Explanation:
It sounds as though the trial is measuring the effect of XYZ on patients' cognition. The researchers have to define how they intend to measure cognition (and changes in it) - so they choose a measure of cognition (likely to be a performance test of some sort). The main measure or test that they choose for measuring cognition is the primary measure of cognition.
Selected response from:

Armorel Young
Local time: 20:42
Grading comment
Thank you very much!
4 KudoZ points were awarded for this answer



Summary of answers provided
3 +7the principal way in which cognition is being assessed
Armorel Young
4using the basic method of measuring
Jack Doughty
3to assess cognitionlirka


  

Answers


10 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5
using the basic method of measuring


Explanation:
the measurement method considered the first and most important one.

Jack Doughty
Local time: 20:42
Native speaker of: Native in EnglishEnglish
PRO pts in category: 80
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12 mins   confidence: Answerer confidence 3/5Answerer confidence 3/5 peer agreement (net): +7
the principal way in which cognition is being assessed


Explanation:
It sounds as though the trial is measuring the effect of XYZ on patients' cognition. The researchers have to define how they intend to measure cognition (and changes in it) - so they choose a measure of cognition (likely to be a performance test of some sort). The main measure or test that they choose for measuring cognition is the primary measure of cognition.

Armorel Young
Local time: 20:42
Native speaker of: Native in EnglishEnglish
PRO pts in category: 20
Grading comment
Thank you very much!

Peer comments on this answer (and responses from the answerer)
agree  Dr. Andrew Frankland
1 hr

agree  Joyce A
1 hr

agree  Goldcoaster
2 hrs

agree  MMUlr: yes - and it's (in this case) most likely the "ADAS-cog" (-> http://www.ncbi.nlm.nih.gov/pubmed/11218956 - direct context: http://clinicaltrials.gov/ct2/show/NCT00675623
2 hrs

agree  Anna Hawkes
4 hrs

agree  Vicky Nash
7 hrs

agree  Phong Le
16 hrs
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2 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5
to assess cognition


Explanation:
It seems that the patient's cognition is being assessed in a trial involving XY and placebo. More context would certainly help.

I think that you may simplify the sentence a bit and just say "to assess cognition".

lirka
Local time: 15:42
Specializes in field
Native speaker of: Native in EnglishEnglish, Native in SlovenianSlovenian
PRO pts in category: 36
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