Login or register (free and only takes a few minutes) to participate in this question.You will also have access to many other tools and opportunities designed for those who have language-related jobs (or are passionate about them). Participation is free and the site has a strict confidentiality policy.
English to English translations [PRO]
Medical - Medical (general) / clinical trial | | English term or phrase: in-house blinding | Double-blind plus in-house blinding
[does this mean at the study site or at home?) |
| | | please see below | Explanation:
In-house blinding means that in addition to the study site personnel and the participant in a clinical trial (double-blind) also the spnsor's reserach personnel (except the statistician creating the schedule) are blinded. Hence also the expression "double-blinded with in-house blinding".
e.g.:
This study will follow the [...] in-house blinding procedure, i.e., besides study center personnel and patients, [...] research personnel (with the exemption of the designated
unblinded statistician) and the CRO conducting the study are also blinded during the screening process of reviewing and finding corrections to the data before the data file is frozen for final statistical analysis and reporting.
http://docs.google.com/viewer?a=v&q=cache:sOkNrcFSuWUJ:www.v...
The gender-stratified randomization schedule was computer-generated by the sponsor. In order to ensure in-house blinding, the schedule was created by an assistant statistician who was otherwise not involved with the study. On the day of surgery, patients were randomized to receive one of three antiemetic treatments before operation: oral aprepitant 40 mg, oral aprepitant 125 mg, or i.v. ondansetron 4 mg. Patient and investigator blinding was maintained with matching placebos.
http://www.medscape.com/viewarticle/560160_2
|
| Selected response from:
 Marga Shaw
Local time: 03:05
| Grading comment Thank you very much!
4 KudoZ points were awarded for this answer |
| |
| Discussion entries: 0 |
|---|
Automatic update in 00:
|
1 hr confidence:   peer agreement (net): +3 please see below
Explanation:
In-house blinding means that in addition to the study site personnel and the participant in a clinical trial (double-blind) also the spnsor's reserach personnel (except the statistician creating the schedule) are blinded. Hence also the expression "double-blinded with in-house blinding".
e.g.:
This study will follow the [...] in-house blinding procedure, i.e., besides study center personnel and patients, [...] research personnel (with the exemption of the designated
unblinded statistician) and the CRO conducting the study are also blinded during the screening process of reviewing and finding corrections to the data before the data file is frozen for final statistical analysis and reporting.
http://docs.google.com/viewer?a=v&q=cache:sOkNrcFSuWUJ:www.v...
The gender-stratified randomization schedule was computer-generated by the sponsor. In order to ensure in-house blinding, the schedule was created by an assistant statistician who was otherwise not involved with the study. On the day of surgery, patients were randomized to receive one of three antiemetic treatments before operation: oral aprepitant 40 mg, oral aprepitant 125 mg, or i.v. ondansetron 4 mg. Patient and investigator blinding was maintained with matching placebos.
http://www.medscape.com/viewarticle/560160_2
| Marga Shaw
Local time: 03:05
Specializes in field
Native speaker of:  German
PRO pts in category: 12
|
| | |
| KudoZ™ translation helpThe KudoZ network provides a framework for translators and others to assist each other with translations or explanations of terms and short phrases. See also: Search millions of term translations  |
| |
The translation workplace 
