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重要靶标


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18:34 Mar 4, 2011
This question was closed without grading. Reason: Other

Chinese to English translations [PRO]
Medical: Pharmaceuticals
Chinese term or phrase: 重要靶标
the whole sentence is "经计算机虚拟筛选,发现系列新奇结构的三萜化合物与多个神经退行性疾病相关的重要靶标结合,如beta-分泌酶等" I don't understand is this phrase mean those triterpenoid compounds can cure the neurodegenerative disease or means they have similar chemical structures or something else? :S
lili5860


Summary of answers provided
5important targets
Weiping Tang
5crucial targets
Xia Kang
4key targetsyongmeili


  

Answers


5 hrs   confidence: Answerer confidence 5/5
important targets


Explanation:
important targets

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Note added at 5 hrs (2011-03-05 00:21:36 GMT)
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意思是说,该化合物能与一些作用靶标结合,而这些靶标是与神经退行性疾病相关的,从而该化合物通过这些作用靶标而可能治疗神经退行性疾病。

Weiping Tang
China
Local time: 07:30
Specializes in field
Native speaker of: Native in ChineseChinese
PRO pts in category: 68
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36 days   confidence: Answerer confidence 5/5
crucial targets


Explanation:
in English paper, crucial targets refer to the target that are very important and key in life activities.

Xia Kang
China
Local time: 07:30
Specializes in field
Native speaker of: Native in ChineseChinese
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72 days   confidence: Answerer confidence 4/5Answerer confidence 4/5
key targets


Explanation:
The word key not only means important but also evokes the image of opening a lock, similar to solving a problem. Neurodegenerative diseases are the problem discussed in the paragraph.

Beta-secretase enzyme is important in secretion of beta-amyloid, the components that form plague lesion in patients of Alzheimer's disease. Thus if some compound can bind to this enzyme (and perhaps inhibit its activity), one hopes that symptoms of the neurodegenerative diseases can be ameliorated or the diseases can be cured. Thus, problem solved.


    Reference: http://www.molecularneurodegeneration.com/content/2/1/22
yongmeili
Local time: 19:30
Native speaker of: Native in ChineseChinese, Native in EnglishEnglish
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