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Located at the crossroads of the main routes linking heavily-industrialized Northern Europe and fast-growing Southern Europe, Lyon occupies a strategic position at the heart of European trade.
The republic of Panama is only a little smaller than South Carolina, but the locals think of their nation as "the crossroads of the world." It lies on trade routes between North and South America, and on the route between the Atlantic and Pacific oceans.
Ancient Mali was at the crossroads of trade.