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Dutch to English translations [PRO]
Medical - Medical: Pharmaceuticals | | Dutch term or phrase: Relevantiegraden | Relevantiegraden toekennen aan interacties en contra-indicaties.
This is the only sentence in the medications part od the doc.
So far I got: Assignation of relevance grade (?) to interactions and contra-indications.
But could it be something like a preferrence mark or smth.? |
| | | clinical importance | Explanation:
could be
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Note added at 4 hrs (2009-07-17 18:00:05 GMT)
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Oog voor lange lijnen. De relevantie van geschiedenis voor het ...De relevantie van geschiedenis voor het integratiedebat in West-Europa = The importance of historical perspectives for the understanding of migration and ...
cat.inist.fr/?aModele=afficheN&cpsidt=15989296
The "relevance" of a drug interaction or contra-indication doesn't make much sense.
--------------------------------------------------
Note added at 5 hrs (2009-07-17 19:16:16 GMT)
--------------------------------------------------
http://rivm.openrepository.com/rivm/bitstream/10029/7295/1/2...
Selectie criteria voor interacties
Hoewel veel ongewenste combinaties van geneesmiddelen in de hierboven genoemde
standaarden beschreven staan, zijn slechts een beperkt aantal geschikt om als uitkomst in dit
onderzoek t te gebruiken. Bruikbare combinaties dienen aan een aantal voorwaarden te
voldoen. De combinatie dient algemeen als ***klinisch relevant*** en ongewenst beschouwd te
worden en eenduidig te zijn.
--------------------------------------------------
Note added at 5 hrs (2009-07-17 19:17:12 GMT)
--------------------------------------------------
http://www.z-index.nl/G-Standaard_beschrijvingen/Technisch/B...
In the reference list:
Stockley Ivan H. Stockley Drug Interactions, a source of adverse interactions, their mechanisms, clinical importance and management, 1991 (ed. 2).
--------------------------------------------------
Note added at 5 hrs (2009-07-17 19:20:36 GMT)
--------------------------------------------------
See "clinical importance score" or "rating"
http://cat.inist.fr/?aModele=afficheN&cpsidt=15967169
Identification of serious drug-drug interactions: Results of the partnership to prevent drug-drug interactions
Auteur(s) / Author(s)
MALONE Daniel C. ; ABARCA Jacob ; HANSTEN Philip D. ; GRIZZLE Amy J. ; ARMSTRONG Edward P. ; VAN BERGEN Robin C. ; DUNCAN-EDGAR Babette S. ; SOLOMON Steven L. ; LIPTON Richard B. ;
Résumé / Abstract
Objective: To develop a list of clinically important drug-drug interactions (DDIs) likely to be encountered in community and ambulatory pharmacy settings and detected by a computerized pharmacy system. Design: Cross-sectional, one-time evaluation. Setting: United States in fall 2001. Participants: An expert panel comprising two physicians, two clinical pharmacists, and an expert on DDIs. Interventions: Systematic review of drug interaction compendia and published literature, ratings (on a 1 to 10 scale) of various clinical aspects of DDIs (e.g., clinical importance, quality and quantity of evidence, causal relationship, risk of morbidity and mortality), and a modified Delphi consensus-building process. Main Outcome Measure: Panelists' opinions about clinical importance of DDIs. Results: The expert panel considered 56 DDIs. Of these, 28 had a mean clinical importance score of 8.0 or more. The ratings for clinical importance ranged from 3.2 to 9.6, with a mean ′ SD of 7.5 ′ 1.5 across the combinations examined. The mean score for the quality of literature suggesting the interaction exists ranged from 1.0 to 9.6, with a mean ′ SD of 5.8 ′ 2.5. In terms of substantiation of the interactions evaluated, the mean ′ SD rating was 6.3 ′ 2.2, with a range from 1.4 to 9.2. Through the modified Delphi process, the panel determined that 25 interactions were clinically important. Conclusion: Using an expert panel and a standard evaluation tool, 25 clinically important drug interactions that are likely to occur in the community and ambulatory pharmacy settings were identified. Pharmacists should take steps to prevent patients from receiving these interacting medications, and computer software vendors should focus interaction alerts on these and similarly important DDIs. |
| Selected response from:
SJLD
Local time: 05:23
| Grading comment Thank you!
4 KudoZ points were awarded for this answer |
| |
| Discussion entries: 0 |
|---|
Automatic update in 00:
|
56 mins confidence:   peer agreement (net): +1
55 mins confidence: clinical importance
Explanation:
could be
--------------------------------------------------
Note added at 4 hrs (2009-07-17 18:00:05 GMT)
--------------------------------------------------
Oog voor lange lijnen. De relevantie van geschiedenis voor het ...De relevantie van geschiedenis voor het integratiedebat in West-Europa = The importance of historical perspectives for the understanding of migration and ...
cat.inist.fr/?aModele=afficheN&cpsidt=15989296
The "relevance" of a drug interaction or contra-indication doesn't make much sense.
--------------------------------------------------
Note added at 5 hrs (2009-07-17 19:16:16 GMT)
--------------------------------------------------
http://rivm.openrepository.com/rivm/bitstream/10029/7295/1/2...
Selectie criteria voor interacties
Hoewel veel ongewenste combinaties van geneesmiddelen in de hierboven genoemde
standaarden beschreven staan, zijn slechts een beperkt aantal geschikt om als uitkomst in dit
onderzoek t te gebruiken. Bruikbare combinaties dienen aan een aantal voorwaarden te
voldoen. De combinatie dient algemeen als ***klinisch relevant*** en ongewenst beschouwd te
worden en eenduidig te zijn.
--------------------------------------------------
Note added at 5 hrs (2009-07-17 19:17:12 GMT)
--------------------------------------------------
http://www.z-index.nl/G-Standaard_beschrijvingen/Technisch/B...
In the reference list:
Stockley Ivan H. Stockley Drug Interactions, a source of adverse interactions, their mechanisms, clinical importance and management, 1991 (ed. 2).
--------------------------------------------------
Note added at 5 hrs (2009-07-17 19:20:36 GMT)
--------------------------------------------------
See "clinical importance score" or "rating"
http://cat.inist.fr/?aModele=afficheN&cpsidt=15967169
Identification of serious drug-drug interactions: Results of the partnership to prevent drug-drug interactions
Auteur(s) / Author(s)
MALONE Daniel C. ; ABARCA Jacob ; HANSTEN Philip D. ; GRIZZLE Amy J. ; ARMSTRONG Edward P. ; VAN BERGEN Robin C. ; DUNCAN-EDGAR Babette S. ; SOLOMON Steven L. ; LIPTON Richard B. ;
Résumé / Abstract
Objective: To develop a list of clinically important drug-drug interactions (DDIs) likely to be encountered in community and ambulatory pharmacy settings and detected by a computerized pharmacy system. Design: Cross-sectional, one-time evaluation. Setting: United States in fall 2001. Participants: An expert panel comprising two physicians, two clinical pharmacists, and an expert on DDIs. Interventions: Systematic review of drug interaction compendia and published literature, ratings (on a 1 to 10 scale) of various clinical aspects of DDIs (e.g., clinical importance, quality and quantity of evidence, causal relationship, risk of morbidity and mortality), and a modified Delphi consensus-building process. Main Outcome Measure: Panelists' opinions about clinical importance of DDIs. Results: The expert panel considered 56 DDIs. Of these, 28 had a mean clinical importance score of 8.0 or more. The ratings for clinical importance ranged from 3.2 to 9.6, with a mean ′ SD of 7.5 ′ 1.5 across the combinations examined. The mean score for the quality of literature suggesting the interaction exists ranged from 1.0 to 9.6, with a mean ′ SD of 5.8 ′ 2.5. In terms of substantiation of the interactions evaluated, the mean ′ SD rating was 6.3 ′ 2.2, with a range from 1.4 to 9.2. Through the modified Delphi process, the panel determined that 25 interactions were clinically important. Conclusion: Using an expert panel and a standard evaluation tool, 25 clinically important drug interactions that are likely to occur in the community and ambulatory pharmacy settings were identified. Pharmacists should take steps to prevent patients from receiving these interacting medications, and computer software vendors should focus interaction alerts on these and similarly important DDIs.
| SJLD
Local time: 05:23
Specializes in field
Native speaker of:  English
PRO pts in category: 8
|
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| Jul 26, 2009 - Changes made by SJLD: | | Created KOG entry | KudoZ term => KOG term |
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