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KAG allo KAG auto

English translation: KIR allele and gene polymorphism group (=KAG)

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GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
Dutch term or phrase:KAG allo KAG auto
English translation:KIR allele and gene polymorphism group (=KAG)
Entered by: orangeworld
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21:29 Feb 6, 2009
Dutch to English translations [PRO]
Medical - Medical (general) / Haematology
Dutch term or phrase: KAG allo KAG auto
A patient had "KAG allo 2 and KAG auto 8" results in a blood test. Could anyone help me with the KAG?
orangeworld
United Kingdom
Local time: 05:23
KIR allele and gene polymorphism group (=KAG)
Explanation:
Allotype and Autotype antibodies to KAG.

See: 1: Mol Immunol. 2005 Feb;42(4):455-7.

KIR allele and gene polymorphism group (KAG).Middleton D.
Northern Ireland Histocompatibility and Immunogenetics Laboratory, City Hospital, Belfast, BT9 7TS Northern Ireland. derek.middleton@bll.n-i.nhs.uk

Recent research presented at this meeting verifies the extent of the polymorphism of KIR genes and their alleles and shows their association with various diseases. Methods were described for the determination of alleles of several of the KIR genes in different populations including a novel allele formed by an unequal recombination event. Associations of KIR genes were found with several diseases: type I diabetes; psoriatic arthritis; and hepatitis C infection. Discussion took place on nomenclature issues of the KIR genes and their alleles, and a website has been developed to collect frequencies of KIR genes and alleles in various diverse populations.

PMID: 15607798 [PubMed - indexed for MEDLINE]

Related ArticlesAllelic polymorphism synergizes with variable gene content to individualize human KIR genotype. [J Immunol. 2002] Genetic diversity of KIR natural killer cell markers in populations from France, Guadeloupe, Finland, Senegal and Réunion. [Tissue Antigens. 2005] Multiple copies of KIR 3DL/S1 and KIR 2DL4 genes identified in a number of individuals. [Hum Immunol. 2003] ReviewGenes influencing innate and acquired immunity in type 1 diabetes and latent autoimmune diabetes in adults. [Ann N Y Acad Sci. 2006] ReviewUnderstanding how combinations of HLA and KIR genes influence disease. [J Exp Med. 2005] » See Reviews... | » See All...

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Note added at 17 days (2009-02-24 18:26:02 GMT)
--------------------------------------------------

Translate it as 'KAG allo -2 and KAG auto-8

Selected response from:

Dr Lofthouse
United Kingdom
Local time: 05:23
Grading comment
Brilliant, thanks!
4 KudoZ points were awarded for this answer

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Summary of answers provided
5KIR allele and gene polymorphism group (=KAG)
Dr Lofthouse


  

Answers


17 days   confidence: Answerer confidence 5/5
KIR allele and gene polymorphism group (=KAG)


Explanation:
Allotype and Autotype antibodies to KAG.

See: 1: Mol Immunol. 2005 Feb;42(4):455-7.

KIR allele and gene polymorphism group (KAG).Middleton D.
Northern Ireland Histocompatibility and Immunogenetics Laboratory, City Hospital, Belfast, BT9 7TS Northern Ireland. derek.middleton@bll.n-i.nhs.uk

Recent research presented at this meeting verifies the extent of the polymorphism of KIR genes and their alleles and shows their association with various diseases. Methods were described for the determination of alleles of several of the KIR genes in different populations including a novel allele formed by an unequal recombination event. Associations of KIR genes were found with several diseases: type I diabetes; psoriatic arthritis; and hepatitis C infection. Discussion took place on nomenclature issues of the KIR genes and their alleles, and a website has been developed to collect frequencies of KIR genes and alleles in various diverse populations.

PMID: 15607798 [PubMed - indexed for MEDLINE]

Related ArticlesAllelic polymorphism synergizes with variable gene content to individualize human KIR genotype. [J Immunol. 2002] Genetic diversity of KIR natural killer cell markers in populations from France, Guadeloupe, Finland, Senegal and Réunion. [Tissue Antigens. 2005] Multiple copies of KIR 3DL/S1 and KIR 2DL4 genes identified in a number of individuals. [Hum Immunol. 2003] ReviewGenes influencing innate and acquired immunity in type 1 diabetes and latent autoimmune diabetes in adults. [Ann N Y Acad Sci. 2006] ReviewUnderstanding how combinations of HLA and KIR genes influence disease. [J Exp Med. 2005] » See Reviews... | » See All...

--------------------------------------------------
Note added at 17 days (2009-02-24 18:26:02 GMT)
--------------------------------------------------

Translate it as 'KAG allo -2 and KAG auto-8



Dr Lofthouse
United Kingdom
Local time: 05:23
Works in field
Native speaker of: Native in EnglishEnglish, Native in ItalianItalian
PRO pts in category: 12
Grading comment
Brilliant, thanks!
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