flavopiridol
Chinese translation: (一种抗癌新药,属黄酮类化合物)
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| 13:59 Dec 4, 2004 |
| English to Chinese translations [PRO] Science - Medical (general) | |||||||
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|  Selected response from: ysun United States Local time: 15:59 | ||||||
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| Summary of answers provided | ||||
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| 3 +1 | 黄素吡多 |
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| 4 | 抗癌新药 |
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| 4 | FYI |
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| 3 | 扶拉平渡 |
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| Discussion entries: 3 | |
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Answers
20 mins confidence: 
peer agreement (net): +1
peer agreement (net): +1黄素吡多 Explanation: ... -------------------------------------------------- Note added at 44 mins (2004-12-04 14:43:31 GMT) -------------------------------------------------- 根据手头的药学词典，flavo-翻译成黄素，-piridol翻译成吡多 |
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1 hr confidence:
扶拉平渡 Explanation: 音译,just like 百服宁. |
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8 hrs confidence:
抗癌新药 Explanation: Flavopiridol是目前进入II期临床的治疗MCL的一种针对细胞周期设计的新药物。它是从印度植物中提炼的植物碱，植物的叶和根是印度应用的草药。美国第一个针对细胞周期进入临床试验的药物。Flavopiridol抑制蛋白激酶cyclin D1及cdk1—4，阻碍细胞从G1期进入S期，引起细胞周期阻滞。同时，它具有直接细胞毒性。因此, Flavopiridol对增殖期和静止期细胞均有作用。 象许多其他药物一样，Flavopiridol通过阻断对细胞分化至关重要的蛋白来发挥作用。自1998年以来，它已被用于肾癌、前列腺癌、结肠癌及其他癌症的临床试验。去年一种新型强效Flavopiridol已展露光芒：该Flavopiridol也可以阻断帮助DNA转录成为信使RNA（messenger RNA，mRNA）的蛋白，这是从基因到蛋白产生的第一步，使所有细胞赖以生存的一个过程。国家癌症研究所的癌症研究者Louis Staudt和他的同事很好奇flavopiridol对于B淋巴细胞的作用。 -------------------------------------------------- Note added at 8 hrs 47 mins (2004-12-04 22:46:57 GMT) -------------------------------------------------- 建议不要翻译，保留原文． |
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2 hrs confidence:
FYI Explanation: 这是一种抗癌新药，恐怕还没有正式的中文译名。除非你得到有关机构的授权，否则即使译成了中文也未必得到公认。故建议不必为它伤脑筋，而保留原文名称。从以下网页上的结构式看，它属于黄酮类衍生物。 http://clltopics.org/Chemo/flavopiridol.htm -------------------------------------------------- Note added at 1 day 5 hrs 34 mins (2004-12-05 19:34:14 GMT) -------------------------------------------------- If I were you, I would translate it as \"细胞周期抑制剂flavopiridol\" so that the readers would know its function as well as the original name. |
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