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English to Dutch translations [PRO] Medical - Medical (general)
English term or phrase:push layer
De uitleg staat eigenlijk in het document, maar wat is de Nederlandse term?
The tablet core of XXX consists of three layers: a push layer and two drug layers. The formulation of the two drug layers is precisely designed to achieve the ascending release profile essential for improvement of safety and tolerability of XXX. The tablet core is surrounded by a semi-permeable membrane. Once the tablet is exposed to the environment of the gastrointestinal tract, water is pulled by osmotic pressure across the membrane into the tablet core. The push layer expands, forcing the drug formulation through the orifices in the tablet dome, and providing delivery of paliperidone in a pre-determined controlled manner.