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gene silencing

Farsi (Persian) translation: خاموشي ژن


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English term or phrase:gene silencing
Farsi (Persian) translation:خاموشي ژن
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13:58 Feb 9, 2010
English to Farsi (Persian) translations [PRO]
Science - Biology (-tech,-chem,micro-)
Additional field(s): Medical (general), Genetics
English term or phrase: gene silencing
Definition from MedicineNet, Inc.:
Gene silencing: A mechanism by which cells shut down large sections of chromosomal DNA. Gene silencing is done by incorporating the DNA to be silenced into a form of DNA called heterochromatin that is already silent. The process of gene silencing is important for the differentiation of many different types of cells.

Example sentence(s):
  • Evidence is emerging that geminiviruses and plant pararetroviruses can interact with the gene silencing system either from introduced DNA constructs or during viral pathogenesis. Some observations suggest there are complex relationships between DNA viral activity, transcriptional and post-transcriptional gene silencing mechanisms.
  • The biggest challenges in the field at the moment are understanding two things: how does DNA methylation participate in gene silencing (and that includes what molecules target the DNA methylation to these promoter regions), and why is the cancer cell doing this? The Thomson Corporation
  • In 2005, Pikaard and his collaborators published research showing that the major function of Pol IV is to generate siRNAs, thereby singling out this RNA polymerase as a potential player in gene silencing. ScienceDaily LLC
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خاموشي ژن
استفاده از روش خاموشی ژن برای درمان بيماری در مغز حيوانات زنده است و ممکن است در آينده برای درمان انسان مورد استفاده قرار گيرد
Selected response from:

Hossein Abbasi Mohaghegh
Grading comment
4 KudoZ points were awarded for this answer


Summary of translations provided
5 +3خاموشي ژن
Hossein Abbasi Mohaghegh


Translations offered

2 hrs   confidence: Answerer confidence 5/5 peer agreement (net): +3
خاموشي ژن

Definition from سرويس خبري ژنتيك:
استفاده از روش خاموشی ژن برای درمان بيماری در مغز حيوانات زنده است و ممکن است در آينده برای درمان انسان مورد استفاده قرار گيرد

Example sentence(s):
  • بررسی خاموشی ژن NANOG در سلول های بنیادی مزانشیمی با استفاده از فناوری RNA تداخلی - iran-eng  
  • تأثير ساختارهاي مختلف القا كننده خاموشي ژن بر ايجاد مقاومت به بيماري ريزومانيا, - ايران داك  
  • خاموشی ژنهای هدف در شرايط in vivo مبدل ساخته است . در مقايسه با دانش فعلی ما در این رشته از علوم، RNAi پیشرفتی بزرگ در زمينه ژنتيک مولکولی گياهی است و پتانسيل زيادی در زمينه کنترل بيان ژنها دا رد و بعنوان ابزاری موثر در جهت ژنوميک کاربردی مطرح است . - بیوتکنولوژی دانش هزار  

در بعضي از مواقع معادل "خاموش كننده" هم براي اين اصطلاح استفاده شده است.
Hossein Abbasi Mohaghegh
Local time: 17:29
Native speaker of: Native in Persian (Farsi)Persian (Farsi), Native in Farsi (Persian)Farsi (Persian)
PRO pts in category: 4

Votes in favor of/against selecting this as the best translation of the term asked
Yes  Salman Rostami: very good!
22 hrs
  -> Thanks!

Yes  Farzad Akmali: خاموشی ژن: زمانی رخ می دهد که ژنی بیان نشود
3 days18 hrs
  -> Thanks!

Yes  Edward Plaisance Jr
5 days
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