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target event goal

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14:00 Mar 5, 2007
This question was closed without grading. Reason: No acceptable answer

English to French translations [PRO]
Mathematics & Statistics
English term or phrase: target event goal
Toujours dans le cadre de la même étude clinique (évaluant l’efficacité, l’innocuité et la tolérance du sorafenib en association avec XXX ou un placebo en première intention dans le traitement du carcinome rénal métastatique) :

"The primary analysis is planned when 113 subjects have experienced a PFS event (radiographic disease progression or death). Two-sided 80% confidence intervals for the PFS hazard ratios of sorafenib + XXX (n=100) vs. sorafenib + placebo (n=50), sorafenib + XXX 10.0 mg/kg QW (n=50) vs. sorafenib + placebo (n=50), and sorafenib + XXX 3.0 mg/kg QW (n=50) vs. sorafenib + placebo (n=50) will be calculated. The target event goal of 113 PFS events (radiographic progression or death) is anticipated 33 months after the first subject is enrolled."

--> "objectif cible de 113 événements relatifs à / affectant la SSP" ?

Par ailleurs, deux "sous-questions" par rapport à cette phrase :
- doit-on dire "les" ou "des" intervalles de confiance à 80% "pour" ou "de(s)" rapports de risque (etc.) seront calculés" ?

- et concernant "PFS hazard ratios" / "PFS events", les traductions "rapport de risque relatif à la survie sans progression" et "événement relatif à / affectant la survie sans progression" sont-elles justes ?

Merci beaucoup d'avance !
Celine Rosselot
Local time: 13:06
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