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SRC-mediated resistance

French translation: résistance médiée par (les tyrosine kinases) SRC

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18:54 Jun 17, 2005
English to French translations [PRO]
Medical - Medical: Pharmaceuticals
English term or phrase: SRC-mediated resistance
About a new drug:
"Provides unprecedented therapeutic success because it offers the most comprehensive inhibition of leukemic signaling pathways due to its greater potency of BCR-ABL inhibition and unique ability to target SRC-mediated resistance"
Samantha Hoffmann
Local time: 05:51
French translation:résistance médiée par (les tyrosine kinases) SRC
Explanation:

Src is the name of a family of tyrosine kinases, a kind of enzymes implied in cell proliferation, adhesion, migration, etc, key processes in tumoral growth.

Src-family kinases : sites et documents francophones
Synonyme(s) MeSH : Famille des kinases src ; Famille des tyrosine kinases src ; Kinases de la famille src ; Tyrosine kinases de la famille src .
www.chu-rouen.fr/ssf/prod/srcfamilykinases.html

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d...
Src family kinases (SFKs) have been implicated as important regulators of ligand-induced cellular responses including proliferation, survival, adhesion and migration.

http://www.hxms.com/je/srcfam.html
Src was the first proto-oncogenic protein described. Since then, many other tyrosine kinases have been identified and characterized. Src remains the ‘grandfather’ non-receptor tyrosine kinase and serves as a prototype for understanding the function and regulation of other tyrosine kinases (refs).
The Src family is composed of nine members in vertebrates.

http://webiologie.free.fr/cellules/membrane/recepteurs_enzym...
Les tyrosine kinases
Les tyrosine kinases constituent une famille d'enzymes très importante dans l'organisme eucaryote. Ces molécules ont en commun la propriété de phosphoryler un résidu tyrosine. Cette méthode est une méthode d'activation ou d'inactivation de certaines voies enzymatiques au sein de la cellule. La plupart de ces kinases sont des récepteurs membranaires.

Selected response from:

Andrés Martínez
Spain
Local time: 05:51
Grading comment
Thank you!
4 KudoZ points were awarded for this answer

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Summary of answers provided
4résistance médiée par (les tyrosine kinases) SRC
Andrés Martínez


  

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24 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5
src-mediated resistance
résistance médiée par (les tyrosine kinases) SRC


Explanation:

Src is the name of a family of tyrosine kinases, a kind of enzymes implied in cell proliferation, adhesion, migration, etc, key processes in tumoral growth.

Src-family kinases : sites et documents francophones
Synonyme(s) MeSH : Famille des kinases src ; Famille des tyrosine kinases src ; Kinases de la famille src ; Tyrosine kinases de la famille src .
www.chu-rouen.fr/ssf/prod/srcfamilykinases.html

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d...
Src family kinases (SFKs) have been implicated as important regulators of ligand-induced cellular responses including proliferation, survival, adhesion and migration.

http://www.hxms.com/je/srcfam.html
Src was the first proto-oncogenic protein described. Since then, many other tyrosine kinases have been identified and characterized. Src remains the ‘grandfather’ non-receptor tyrosine kinase and serves as a prototype for understanding the function and regulation of other tyrosine kinases (refs).
The Src family is composed of nine members in vertebrates.

http://webiologie.free.fr/cellules/membrane/recepteurs_enzym...
Les tyrosine kinases
Les tyrosine kinases constituent une famille d'enzymes très importante dans l'organisme eucaryote. Ces molécules ont en commun la propriété de phosphoryler un résidu tyrosine. Cette méthode est une méthode d'activation ou d'inactivation de certaines voies enzymatiques au sein de la cellule. La plupart de ces kinases sont des récepteurs membranaires.



Andrés Martínez
Spain
Local time: 05:51
Specializes in field
Native speaker of: Spanish
PRO pts in category: 4
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