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down-regulation


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11:09 Nov 8, 2009
This question was closed without grading. Reason: Other

English to French translations [PRO]
Science - Medical (general) / fécondation in vitro
English term or phrase: down-regulation
down-regulation using long GnRH-agonist protocol
Irène Guinez
Spain
Local time: 22:24


Summary of answers provided
4 +2régulation négative
Helen Munduteguy
4Désensibilisationmdcdc
4action de freinage ou freinage (simplement)
François Begon


  

Answers


4 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +2
régulation négative


Explanation:
s'il s'agit bien de l'expression ou de la fonction d'une protéine ou d'un gène

123bio.net - Revues - RCPGs et signalisation
La régulation négative ou "down regulation" se caractérise par une perte du nombre .... La "down regulation" du récepteur b2-adrénergique par la protéine ...
www.123bio.net/revues/psarret/ii4.html

down-regulation : Dictionnaire pharmaceutique - Pharmacologie et ...
s.f. [down-regulation]. Terme anglo-saxon signifiant régulation négative. Utilisé pour exprimer la diminution d'une réponse physiologique suite à un ...
www.informationhospitaliere.com/pharma-4000-down-regulation... -

Helen Munduteguy
France
Local time: 22:24
Specializes in field
Native speaker of: Native in EnglishEnglish, Native in FrenchFrench
PRO pts in category: 20

Peer comments on this answer (and responses from the answerer)
agree  Drmanu49: Depending on the settings yes.
59 mins

agree  xxxLionel_M: Sans plus de contexte oui, mais attention, il pourrait s'agir de "rétrocontrole" négatif
1 hr
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7 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5
action de freinage ou freinage (simplement)


Explanation:
le freinage d'une glande endocrine est couramment utilisé

François Begon
France
Local time: 22:24
Specializes in field
Native speaker of: Native in FrenchFrench
PRO pts in category: 313
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7 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5
Désensibilisation


Explanation:
Définit en pharmacologie comme etant l'atténuation de la réponse induite par un agoniste : « down regulation »
* diminution du nombre de récepteurs
* découpage fonctionnel entre le récepteur et l'effecteur
qui est l'atténuation

More information would be useful and the answer proposed by Helen could be better.

mdcdc
Local time: 13:24
Works in field
Native speaker of: Native in FrenchFrench
PRO pts in category: 74
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