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English to German translations [PRO]
Medical - Genetics / oncology, sarcomas, chemotherapy, trabectedin | | English term or phrase: low BRCA1 along with high ERCC1 and/or XPG | A retrospective study indicates that a composite signature based on DNA repair profile, **including low BRCA1 along with high ERCC1 and/or XPG**, identifies a highly sensitive population with highly improved treatment outcome. This signature could be used for patient’s enrichment studies in sarcoma and on other malignancies sensitive to trabectedin.
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Ist hier eine "niedrige BRCA1- und hohe ERCC1-/XPG-Expression" gemeint?
"Eine retrospektive Studie weist darauf hin, dass mit einer ??? Signatur basierend auf einem DNA-Reparaturprofil **mit niedriger BRCA1- und hoher ERCC1-/XPG-Expression*** eine hoch sensitive Population identifiziert und dadurch das Therapieoutcome signifikant verbessert werden kann."
Vgl. http://haematologie-onkologie.universimed.com/artikel/dna-bl... |
|  VeronikaNeuholdKudoZ activityQuestions: 857 ( 1 open) ( 1 without valid answers) ( 32 closed without grading) Answers: 187
Austria
| | Local time: 14:25
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| | Selected response from:
Anne Schulz
Local time: 14:25
| Grading comment | 4 KudoZ points were awarded for this answer |
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| Discussion entries: 0 |
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Automatic update in 00:
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1 hr confidence:   peer agreement (net): +3 | low brca1 along with high ercc1 and/or xpg niedrige BRCA1- und hohe ERCC1- u./o. XPG-Expression
Explanation:
Ja, ich würde hier auch "Expression" ergänzen.
| Anne Schulz
Local time: 14:25
Works in field
Native speaker of:  German
PRO pts in category: 20
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| | Notes to answerer
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