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English to German translations [PRO]
Medical - Medical: Pharmaceuticals / Arzneimittelstudie (Mammakarzinom) | | English term or phrase: clearance and apparent Vd | Overall objective tumor response rates (CR, PR) and disease control rate (CR, PR, SD) will be calculated along with 95% confidence intervals. The duration of objective tumor response, duration of CR, duration of PR, duration of SD, and time to disease progression will be determined for the expanded dose group only using the Kaplan-Meier procedure.
Safety observations and measurements including study drug exposure, adverse events, laboratory data, vital signs, ECG, and ECOG performance status will be summarized and presented in tables and listings.
PK parameters will be calculated using non-compartmental and/or compartmental models and PK parameters (if possible, Cmax, Tmax, AUC, t½, ***clearance and apparent Vd *** will be summarized and presented. The mean (± STDEM) concentration-time profiles of both AV-951 and paclitaxel will be presented for each dose. |
| | | Clearance und Verteilungsvolumen | Explanation:
"Volume of distribution" und "apparent volume of distribution" werden synonym verwendet. Wir sagen "Verteilungsvolumen". "Clearance" bleibt meist unübersetzt.
Dazu gehören die beiden Grössen «Verteilungsvolumen» und «Clearance», die zu den Basisinformationen gehören, die uns zur Pharmakokinetik eines Medikamentes ...
www.infomed.org/pharma-kritik/pk11b-96.html
Ein Teil der Variabilität der Parameter Clearance, peripheres Verteilungsvolumen sowie Geschwindigkeitskonstante und PC in das im-Kompartiment konnte duch ...
sundoc.bibliothek.uni-halle.de/diss-online/07/07H049/index.htm |
| Selected response from:
Susanne Rindlisbacher
| Grading comment Danke Susanne et al.
4 KudoZ points were awarded for this answer |
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The translation workplace 
peer agreement (net): -2
