German translation: (Bestimmung des) Knochen-Isoenzyms/Knochen-AP
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Explanation: ... ist meine Vermutung ohne näheren Kontext.
Ist die AlkPhos im Blut erhöht kann das auf eine Erkrankung in verschiedenen organen hinweisen. Zur genaueren Abklärung werden Knochen- oder Leber-Isoenzyme getestet.
Die Bestimmung der Aktivität z. B. des Leber- bzw. des Knochenisoenzyms ist von besonderer diagnostischer Bedeutung bei der Untersuchung von Erkrankungen der Leber bzw. des Knochenenzyms. Die Erkrankungen bewirken einen Anstieg der AP-Aktivität im Plasma, da unter diesen Voraussetzungen von der Leber bzw. den Knochen in verstärktem Maße Alkalische Phosphatase an das Plasma abgegeben wird. Der Anstieg der AP-Aktivität des Leber- oder des Knochen-Isoenzyms im Plasma kann demnach dazu dienen, eine Erkrankung dieser Gewebe zu erkennen. http://www.patent-de.com/19921203/DE4117619A1.html
Alkaline phosphatase is an enzyme found in all tissues. Tissues with particularly high concentrations of ALP include the liver, bile ducts, placenta, and bone.
Damaged or diseased tissue releases enzymes into the blood, so serum ALP measurements can be abnormal in many conditions, including bone disease and liver disease. Serum ALP is also increased in some normal circumstances (for example, during normal bone growth) or in response to a variety of drugs.
There are multiple varieties of ALP (Alkaline phosphatase) , called isoenzymes. Different types of isoenzymes, each with different structures, are found in different tissues (for example, liver and bone ALP isoenzymes have different structures) and can be quantified separately in the laboratory. To differentiate the location of damaged or diseased tissue in the body, ALP isoenzyme testing must be done. http://arthritis-symptom.com/procedures/alk-phos.htm
My concern is that the term "bone isomer" is non-sensical whilst I agree with Andrea that most likely ref. made here is to "alk. phosphatase bone isoenzyme". However, this should be pointed out to/queried with the author/client as "isomer" and "isoenzyme" are different by definition.
alk phos, meaning alkaline phosphate by any chance? Isomer seems to refer to some standardization? But a bit more context might be helpful?
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Answers
33 mins confidence: peer agreement (net): +3
(Bestimmung des) Knochen-Isoenzyms
Explanation: ... ist meine Vermutung ohne näheren Kontext.
Ist die AlkPhos im Blut erhöht kann das auf eine Erkrankung in verschiedenen organen hinweisen. Zur genaueren Abklärung werden Knochen- oder Leber-Isoenzyme getestet.
Die Bestimmung der Aktivität z. B. des Leber- bzw. des Knochenisoenzyms ist von besonderer diagnostischer Bedeutung bei der Untersuchung von Erkrankungen der Leber bzw. des Knochenenzyms. Die Erkrankungen bewirken einen Anstieg der AP-Aktivität im Plasma, da unter diesen Voraussetzungen von der Leber bzw. den Knochen in verstärktem Maße Alkalische Phosphatase an das Plasma abgegeben wird. Der Anstieg der AP-Aktivität des Leber- oder des Knochen-Isoenzyms im Plasma kann demnach dazu dienen, eine Erkrankung dieser Gewebe zu erkennen. http://www.patent-de.com/19921203/DE4117619A1.html
Alkaline phosphatase is an enzyme found in all tissues. Tissues with particularly high concentrations of ALP include the liver, bile ducts, placenta, and bone.
Damaged or diseased tissue releases enzymes into the blood, so serum ALP measurements can be abnormal in many conditions, including bone disease and liver disease. Serum ALP is also increased in some normal circumstances (for example, during normal bone growth) or in response to a variety of drugs.
There are multiple varieties of ALP (Alkaline phosphatase) , called isoenzymes. Different types of isoenzymes, each with different structures, are found in different tissues (for example, liver and bone ALP isoenzymes have different structures) and can be quantified separately in the laboratory. To differentiate the location of damaged or diseased tissue in the body, ALP isoenzyme testing must be done. http://arthritis-symptom.com/procedures/alk-phos.htm
Andrea Winzer United States Local time: 20:51 Specializes in field Native speaker of: German PRO pts in category: 76
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Vielen Dank!
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