Paulinho, confesso que "ressecamento" também me ocorreu, até porque a Wiki tem um artigo sobre o termo em medicina:
Defatting is the chemical dissolving of dermal lipids, from the skin, on contact with defatting agents. This can result in water loss from the affected area and cause the whitening and drying of the skin which may result in cracking, secondary infection and chemical irritant contact dermatitis.[1]
Defatting is caused by the exposure of human skin to a chemical substance, including alcohols, detergents, chemical solvents and motor oil. Aliphatic compounds (commonly found in kerosene) cause defatting action, with lower-boiling point aliphatics having the greatest defatting action and therefore the most potential to cause dermatitis. Aromatic compounds, such as styrene also have a defatting capacity.[1]
https://en.wikipedia.org/wiki/Defatting_(medical)Poderia ser ainda uma desidratação grave da pele.