| GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW) | | English term or phrase: | protofected | | Russian translation: | внедренные в митохондрии | | Entered by: | Igor_2006 |
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English to Russian translations [PRO] Science - Genetics | | English term or phrase: protofected | Если protofection переводить по аналогии с transfection - протофекция, то как быть с protofected?
Clearly delineate the successful cleavage of native genes by ***protofected*** restriction enzymes.
Спасибо. |
| | | генно-инженерные рестриктазы, экспрессирующиеся в митохондриях | Explanation: Мне кажется, что ответ Алекса не совсем точен. "protofection" означает внедрение генно-инженерных структур именно в митохондрии, а не вообще в клетки.
... "ProtoFection" uses recombinant human mitochondrial transcription factor A (TFAM) engineered with an N-terminal protein transduction domain (PTD) followed by the SOD2 mitochondrial localization signal (MLS) to deliver mtDNA cargo to the mitochondria of living cells. MTD-TFAM (MTD = PTD + MLS = "mitochondrial transduction domain") binds mtDNA and rapidly transports it across plasma membranes to mitochondria. For therapeutic proof-of-principle we tested ProtoFection technology in Parkinson's disease cybrid cells ... |
| Selected response from: Igor_2006 Russian Federation Local time: 06:39
| Grading comment Спасибо! 4 KudoZ points were awarded for this answer |
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