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12:03 Mar 23, 2007
English to Russian translations [PRO] Medical - Medical: Pharmaceuticals
English term or phrase:dose recovered
The apparent volume of distribution is 83 l. Miglustat does not bind to plasma proteins. Biotransformation results in a number of metabolites which are excreted in both urine and faeces. The major route of excretion is via the urine, with a mean of 82.8% of the administered dose recovered. Faecal excretion accounted for a mean of 11.9% of the dose administered. Apparent oral clearance (CL/F) is 230 ± 39 ml/min. The average half life is 6 – 7 hours.