| English term or phrase: Equimolar given in relation | Obtaining of crude Topiramate
Highly reactive. It mostly forms the 2,3,4,5-Bis-O-(1- methylethylidene)-β-D-fructopyranose sulfonyl chloride (TP-2). *Equimolar given in relation* to 2,3,4,5-di-O- Isopropylidene-ß-D-fructopyranose (TP-1). Potential quantities of the unreacted sulfuryl chloride are washed off with water during the extraction in
water/dichloromethane system used to isolate the
product. |
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