| English term or phrase: IRIS Summary | On the basis of epidemiologic studies on subjects occupationally exposed to TEA reversible, temporary blurring of vision manifesting itself by deterioration of visual activity, perception of contrast sensitivity and increase of corneal thickness, corneal edema as well as formation of subepithelial microcysts were revealed. Blurred vision is a typical symptom of triethylamine effect on humans.
According to *IRIS Summary* (Lynch D.W. et al., Toxicol. Indus. Health., 1990, 6 (3/4), 403-
414):
NOEL = 247 ppm
Rats; exposure by inhalation: 6 hours/day, 5 days/week, for 28 weeks, dose 247 ppm
According to the ICH guidelines the limit for triethylamine is calculated as per below equations: |
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