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RISC loading complex (RlC)


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11:19 Feb 23, 2011
This question was closed without grading. Reason: Other

English to Serbian translations [PRO]
Medical - Medical (general) / molecular microbiology
English term or phrase: RISC loading complex (RlC)
The relative thermodynamic stabilities of the 5′ ends
of the two siRNA strands in the duplex determines the
identity of the guide and passenger strands22–24. In flies,
this thermodynamic difference is sensed by the dsRNAbinding
protein R2D2, the partner of DCR-2 and a
component of the RISC loading complex (RlC)25,2
Fedja Imamovic
Bosnia and Herzegovina
Local time: 16:58

Summary of reference entries provided
RISC (RNA-induced silencing complex), RLC (RISC-loading complex)
Gordana Sujdovic

  

Reference comments


1 day4 hrs peer agreement (net): +1
Reference: RISC (RNA-induced silencing complex), RLC (RISC-loading complex)

Reference information:
http://www.phosphosite.org/proteinAction.do?id=15651&showAll...

Protein names:

Recommended name:
RISC-loading complex subunit TARBP2
Alternative name(s):
TAR RNA-binding protein 2
Trans-activation-responsive RNA-binding protein
http://www.uniprot.org/uniprot/Q15633


In humans, Ago2 is loaded with miRNAs by the action of a specialized assembly called the RISC-loading complex (RLC), comprising the proteins Ago2, Dicer, ...
www.mendeley.com/.../in-vitro-reconstitution-of-the-human-r...

What does RISC stand for

http://www.acronymfinder.com/RNA-Induced-Silencing-Complex-(...

RNA-induced silencing complex
Definition: A ribonucleoprotein complex that contains members of the Argonaute family of proteins, small interfering RNAs (siRNAs) or microRNAs (miRNAs), and miRNA or siRNA-complementary mRNAs, in addition to a number of accessory factors. The RISC complex is involved in posttranscriptional repression of gene expression through downregulation of translation or induction of mRNA degradation.

Gordana Sujdovic
Serbia
Specializes in field
Native speaker of: Native in SerbianSerbian
PRO pts in category: 4

Peer comments on this reference comment (and responses from the reference poster)
agree  b79: excellent
2 days3 hrs
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