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English to Spanish translations [PRO] Science - Biology (-tech,-chem,micro-) | | English term or phrase: epitopic core regions | In connection with expression embodiments to prepare recombinant proteins and peptides, it is contemplated that longer DNA segments will most often be used, with DNA segments encoding the entire peptide sequence being most preferred. However, it will be appreciated that the use of shorter DNA segments to direct the expression of crystal peptides or epitopic core regions, such as may be used to generate anti-crystal protein antibodies, also falls within the scope of the invention. DNA segments that encode peptide antigens from about 8 to about 50 amino acids in length, or more preferably, from about 8 to about 30 amino acids in length, or even more preferably, from about 8 to about 20 amino acids in length are contemplated to be particularly useful.
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| Gabriel RKudoZ activityQuestions: 262 ( 2 open) ( 1 closed without grading) Answers: 0
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| | Selected response from:
Liliana Marquesini
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14 mins confidence:  
6 mins confidence:  peer agreement (net): +1 regiones nucleares epitópicas / del epítopo
Explanation: Se refiere a las regiones que conforman el núcleo epitópico. Por ejemplo, en QPEQPFP, el tripéptido PEQ és el núcleo del epítopo.
-------------------------------------------------- Note added at 1 hr (2012-02-11 16:26:10 GMT) --------------------------------------------------
Ejemplos:
"Se pueden también identificar epítopos procedentes de secuencias de aminoácidos primarios sobre la base de la hidrofobicidad. A estas regiones se hace referencia también como “regiones nucleares epitópicas”."
http://www.espatentes.com/pdf/2255502_t3.pdf
"Sin embargo, se apreciará que la utilización de segmentos de
ADN más cortos para dirigir la expresión de los péptidos LTBP-3 o de las regiones nucleares epitópicas, tal como puede utilizarse para generar anticuerpos anti-LTBP-3, queda también dentro del alcance de la
presente invención."
http://www.espatentes.com/pdf/2139889_t3.pdf
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