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21:39 Mar 24, 2007
This question was closed without grading. Reason: Answer found elsewhere
English to Spanish translations [PRO] Medical - Livestock / Animal Husbandry / feline diseases
English term or phrase:normal T expressed and secreted (RANTES)
...control tissues in yhe cytokines IL-1b, IL-2, IL-4, IL-6, IL-12p40, IL-18, IFN-y, IFN-a, and regulated on activation, normal T expressed and secreted (RANTES)
Regulated upon Activation, Normal T-cell Expressed, and Secreted or RANTES is an 8kDa protein classified as a chemotactic cytokine or chemokine. It has recently been renamed CCL5. RANTES is chemotactic for T cells, eosinophils and basophils and plays an active role in recruiting leukocytes into inflammatory sites. With the help of particular cytokines (i.e. IL-2 and IFN-γ) that are released by T cells, RANTES also induces the proliferation and activation of certain natural killer (NK) cells to form CHAK (CC-Chemokine-activated killer) cells. It is also a HIV-suppresive factor released from CD8+ T cells. This chemokine has been localized to chromosome 17 in humans.
Rodarte United States Local time: 02:15 Native speaker of: Spanish