TRPM8, transient receptor potential melastatin subfamily channel 8
Spanish translation: canal 8 (subfamilia melastatatina)) potencial de receptor transitorio
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| 01:09 May 19, 2005 |
| English to Spanish translations [PRO] Science - Medical: Pharmaceuticals / Assay | |||||||
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|  Selected response from: carlie602 | ||||||
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| 4 | canal (iónico) TRP de la subfamilia de la melastatina nº 8 |
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| 3 | canal 8 (subfamilia melastatatina)) potencial de receptor transitorio |
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| Discussion entries: 1 | |
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Answers
1 hr confidence: 
| trpm8, transient receptor potential melastatin subfamily channel 8 canal 8 (subfamilia melastatatina)) potencial de receptor transitorio Explanation: me parece lo mas cerca |
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6 hrs confidence:
| trpm8, transient receptor potential melastatin subfamily channel 8 canal (iónico) TRP de la subfamilia de la melastatina nº 8 Explanation: Yo abreviaría "transient receptor potencial" con sus siglas en inglés (TRP)para evitar un término muy largo. La traducción completa sería: "canal iónico de potencial receptor transitorio de la subfamilia de la melastatina, miembro nº 8". http://srs.sanger.ac.uk/srsbin/cgi-bin/wgetz?[omim-ID:606678... *606678 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 8; TRPM8 belongs to the 'long' or melastatin subfamily of TRP channels, http://www.iuphar-db.org/iuphar-ic/TRPM/TRPMIntro.pdf TRANSIENT RECEPTOR POTENTIAL CHANNELS The mammalian TRP (transient receptor potential) ion channels are named after the role of the channels in Drosophila phototransduction. (...) The mammalian TRP channel family – comprising three subfamilies TRPC, TRPV and TRPM... (...) The TRPM channels The TRPM subfamily has eight members divided into four groups. Constituents of the first subgroup include the founding member TRPM1 (melastatin or LTRPC1) and TRPM3 (KIAA1616 or LTRPC3). TRPM7 (TRP-PLIK, ChaK(1), LTRPC7)and TRPM6 (ChaK2) belong to the second group. TRPM2 (TRPC7 or LTRPC2) and ***TRPM8 (Trp-p8 or CMR1)*** form the third group. TRPM8 is a 1104aa protein that does not appear to contain associated enzymatic domains. TRPM8 is non-selective, outwardly rectifying channel ***that can be activated by cold (8–28°C) or cooling compounds such as menthol***. This channel is expressed in small-diameter primary sensory neurones, where it presumably functions as a thermosensor 47,48. TRPM8 is also expressed in prostate epithelium, where its physiological function is unknown 49. and adult tumours. La percepción del dolor y la temperatura (...)***Este receptor, que forma parte de la familia de canales iónicos llamados ***canales de potencial receptor transitorio (TRP)***, ha sido rebautizado TRPV1. www2.unil.ch/edab/es/publications/EuroBRAIN_10_es.pdf Lamento la parrafada para leer, pero era necesario documentar bien el término. :-) |
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