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Medical - Medical: Pharmaceuticals / farmacología | | English term or phrase: time of free drug | ¡Hola!
Me esta costando traducir la siguiente oración, especialmente a partir de 'of 40% time of free drug'. El contexto es un documento clínico (una justificación de una modificación del prospecto) sobre un antibiótico, meropenem. Ahí va la oración:
The rationale for the dose recommendation for Pseudomonas aeruginosa is based on pharmacodynamic data derived from patients indicating that this dose achieves a high probability of attainment of the pharmacodynamic target of 40% time of free drug above an MIC of 2 μg/mL over the 8-hour dosing interval.
¿Cómo traduciríais esa última parte? ¿Del 40%...?
Agradezco de antemano vuestra ayuda. |
| Esther YáñezKudoZ activityQuestions: 14 (none open) Answers: 3
Spain
| | Local time: 18:04
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| | Spanish translation:concentración del fármaco libre superior a la CIM de 2 µg/mL durante un 40% del tiempo | Explanation:
Un intento:
… datos obtenidos de pacientes que indican que con esta dosis existe una alta probabilidad de conseguir el objetivo farmacodinámico de concentración del fármaco libre superior a la concentración inhibidora mínima (CIM) de 2 µg/mL durante un 40% del tiempo con el intervalo de dosificación de 8 horas. |
| Selected response from:
gnmhe
Local time: 18:04
| Grading comment ¡Muchas gracias!
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