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English to Tamil translations [PRO]
Medical - Medical: Pharmaceuticals / medical research | | English term or phrase: Washout period | | subject's ability to meet the randomization criteria can be influenced by a wash out period for current medications |
| | | மருந்தின் செறிவு வெளியேற்றப்படுகிற காலகட்டம் | Explanation:
நோயாளிக்கு முதல் சிகிச்சையில் வழங்கப்பட்ட மருந்து குறைந்தபட்ச செறிவுக்கு குறைகிற வரையில் இரண்டாவது சிகிச்சையை ஆரம்பிக்காமல் காத்திருக்கிற ஓய்வு காலகட்டம் Washoutperiod என அழைக்கப்படுகிறது.
நோயாளிக்கு இரண்டு சிகிச்சை காலகட்டங்களுக்கு இடையே வேறு சிகிச்சை எதுவும் வழங்கப்படாமல் இருக்கும் ஓய்வு காலகட்டம் Washoutperiod ஆகும். அதாவது, இந்த ஓய்வு காலகட்டம் என்பது முதல் சிகிச்சையில் வழங்கப்பட்ட மருந்தின் செறிவு அடுத்த சிகிச்சை காலகட்டத்திற்கு செல்லாதவாறு வெளியேற்றப்படும் காலஅளவுக்கு நீடிக்கும். அல்லது மருந்து குறைந்தபட்ச செறிவுக்கு குறைகிற வரையிலான காலகட்டம் Washoutperiod என அழைக்கப்படுகிறது.
http://www.allinterview.com/showanswers/156904.html
Re: what is washout period? Answer
# 1
Washoutperiod is the defined as rest period b/w two
treatment periods for which the effect of one treatment
administered at one dosing period does not carry over to the next.
More clearly,
Normally in clinical trials drug is given at certain intervals .
For example in a study the volunteer took dose 50mg of drug,if the drug has half life of 2.5 hrs...,(that means ittakes 2.5 hrs of time for the drug concentration come to 25mg half of its concentration)
First period Initial drug dose given is 50mg,
Finally the minimum amount accepatable, so that another 50 mg of drug dose can be given is 0.00125mg.
It will take at least 38.219 hrs for that drug to be in theleast concentration (ie.0.00125 or 99.9% of drug dose 1 to be eliminated). 50mg,25mg,12.5mg,6.5mg and
......................................................upto
0..00125mg is the least concentration ie 99.9% of drug
eliminated and does not have carryover effect and now
another drug of 50 mg can be given so that the effect of
first dose of drug cannot be seen on second dose of drug.
This period where the drug is reduced to least
concentration is called the washout period.
So that it does not have carry over effect when again
another 50mg drug is given.
Re: what is washout period? Answer
# 2
A period in a clinical study during which subjects receive no treatment for the indication under study and the effects of a previous treatment are eliminated (or assumed to be eliminated).
A period of time to allow one agent to clear the body before another agent can be safely introduced. Washout periods vary depending on the agents involved.
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| Selected response from:
  AR Ashok kumar
India
Local time: 05:39
| Grading comment Thank you very much for your help.
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16 mins confidence:   peer agreement (net): -1 | washout period ஆரம்ப காலகட்டம்
Explanation:
Run-in period is a period before a clinical trial is commenced when no treatment is given. The clinical data from this stage of a trial are only occasionally of value but can serve a valuable role in screening out ineligible or non-compliant participants, in ensuring that participants are in a stable condition, and in providing baseline observations. A run-in period is sometimes called a washout period if treatments that participants were using before entering the clinical trial are discontinued.
See: http://en.wikipedia.org/wiki/Run-in_period
முதலில் யாரையெல்லாம் ஆய்வுக்கு அனுமதிப்பது என்பதை பார்க்க நடத்தப்படும் முன் சோதனைகளின் கால கட்டம்.
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5 hrs confidence: peer agreement (net): -1 | washout period எம்மருந்தும் உட்கொள்ளாக் காலம் அல்லது எம்மருந்தும் உட்கொள்ளா இடைவெளி
Explanation:
washout period - என்பதற்கு ‘ஒன்றுமில்லாக்காலம்’ என அர்த்தம் கொள்ளுதல் சரியே. ஆனால், இச்சொல் மருத்துவ ஆய்வுகளில் வேறுபட்ட செயல் முறைகளுக்குத்தக்கவாறு உபயோகப்படுத்தப் படுகிறது.
இங்கு கொடுக்கப்பட்டுள்ள கேள்வி Crossover trials களுக்குத் தொடர்பானது எனவே நான் கருதுகிறேன். ஆதலால் ‘எம்மருந்தும் உட்கொள்ளா இடைவெளி’ பொருந்தும் என எண்ணுகிறேன்.
பார்க்க:
Run-in period is a period before a clinical trial is commenced when no treatment is given. The clinical data from this stage of a trial are only occasionally of value but can serve a valuable role in screening out ineligible or non-compliant participants, in ensuring that participants are in a stable condition, and in providing baseline observations. A run-in period is sometimes called a washout period if treatments that participants were using before entering the clinical trial are discontinued.
http://en.wikipedia.org/wiki/Run-in_period
Crossover trials are designed so that each recruited patient
receives both active and control treatments in either order
for a specified duration, with a ‘washout’ period between
treatments when no treatment is administered.
http://en.wikipedia.org/wiki/Run-in_period
Reference: http://www.richmondpharmacology.com/downloads/Publications/C...
| champ3747
India
Local time: 05:39
Meets criteria
Native speaker of:  Tamil
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