Finnish to English translations [PRO] Medical - Medical: Pharmaceuticals | | Finnish term or phrase: kulkeutuminen | Would you please advise me what is "kulkeutuminen" - pathway, transfer, metabolic route? Thank you in advance.
1. Palaverin tarkoituksena oli pohtia COMT-estäjien rakenteen ja fysikokemiallisten ominaisuuksien vaikutusta niiden kulkeutumiseen soluihin ja lipofiilisiin kudoksiin. (1. The purpose of the meeting was to discuss the effect of the structure and physicochemical properties of the COMT inhibitors ... ??? PLEASE HELP!)
2. Kulkeutumiseen vaikuttavien fysikokemiallisten parametrien määrittely: |
| Jonna LahteenmakiKudoZ activityQuestions: 26 (none open) ( 1 closed without grading) Answers: 30 Finland
| | Local time: 03:16
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| | English translation:distribution, absorption | Explanation: Toksikologimieheni mielestä paras tapa ilmaista lause olisi
The purpose of the meeting was to discuss the effect of the structure and physicochemical properties of the COMT inhibitors on their absorption into cells and distribution to lipofilic/lipophyllic tissues
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| Selected response from: tarja Local time: 10:16
| Grading comment Thank you, Tarja! I have done intensive background reading and also consult a few doctors here in Atlanta and found your answer most accurate and suitable for my document. 4 KudoZ points were awarded for this answer |
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| Discussion entries: 0 |
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Automatic update in 00:
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30 mins confidence:  peer agreement (net): +1
18 mins confidence:   transfer
Explanation: Tätä itse käyttäisin.
-------------------------------------------------- Note added at 1 hr (2008-10-07 16:22:30 GMT) --------------------------------------------------
Online-sanakirjoista on pula, itse en ole löytänyt yhtään hyvää. Jos jollakulla on vinkkejä, otetaan vastaan.
IMHO passage on enemmän kauttakulkua, transfer viittaa enemmän siirtymiseen. Sanotaanhan esimerkiksi DNA transfer into cells ja transfer of genetic material into cells.
http://deposit.ddb.de/cgi-bin/dokserv?idn=971267650&dok_var=...
-------------------------------------------------- Note added at 2 hrs (2008-10-07 17:14:37 GMT) --------------------------------------------------
Catechol-O-methyltransferase (COMT) is one of the main enzymes responsible for the metabolism of levodopa, dopamine, other catecholamines (adrenaline and noradrenaline), and their metabolites. COMT catalyzes the transfer of a methyl group from S-adenosyl-L-methionine (SAM) to the hydroxyl group of catecholamines. COMT is widely distributed throughout the body including central nervous system neurons and glia, but not nigrostriatal dopamine neurons.
-------------------------------------------------- Note added at 2 hrs (2008-10-07 17:42:25 GMT) --------------------------------------------------
http://www.holisticonline.com/Remedies/Parkinson/pd_COMT.htm
ja
http://www.parkinsonsdecisionaid.eu.com/medInfo/COMTinhibito...
jossa käytetään deliver ja transport -verbejä.
-------------------------------------------------- Note added at 2 hrs (2008-10-07 17:44:57 GMT) --------------------------------------------------
Myös distribute-verbiä on käytetty esimerkissä.
|  Alfa Trans Local time: 03:16 Works in field Native speaker of: Finnish PRO pts in category: 4
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| | Notes to answerer
Asker: Kiitos, Marju!
Asker: Marju, do you know any available and reliable medical FI<>EN dictionaries/glossaries on-line, paitsi MOT? Thank you.
Asker: Kiitos!
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6 hrs confidence:  peer agreement (net): +1 distribution, absorption
Explanation: Toksikologimieheni mielestä paras tapa ilmaista lause olisi
The purpose of the meeting was to discuss the effect of the structure and physicochemical properties of the COMT inhibitors on their absorption into cells and distribution to lipofilic/lipophyllic tissues
| tarja Local time: 10:16 Native speaker of: Finnish PRO pts in category: 8
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| | Grading comment | Thank you, Tarja! I have done intensive background reading and also consult a few doctors here in Atlanta and found your answer most accurate and suitable for my document. |
| Notes to answerer
Asker: I am not sure that the word "kulkeutuminen" could be transalted into English as "distribution, absorption". Thank you.
Asker:
Asker: sorry, should be read "translated ..."
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