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bypasseante

English translation: bypass agent

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GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)

French term or phrase:	bypasseante
English translation:	bypass agent
Entered by:	Jason Willis-Lee

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10:18 Jul 25, 2007

French to English translations [PRO]
Medical - Medical: Health Care

French term or phrase: bypasseante

Verbatim physician responses regarding heamophilia, recombinant factor VIII, etc. It looks poorly expressed but does it mean it can be used in cases of bypass surgery? TIA, Jason.

Efficace dans l'hémophilie acquise AMM en France
prophylaxie
Plasmatique, deuxième choix, risque de rappel
Utilisation dans le cadre de patients ayant developpe des inhibiteurs
**bypasseante**

Jason Willis-Lee KudoZ activity Questions: 1105 (none open) (1 without valid answers) (30 closed without grading) Answers: 112
Local time: 02:42

has factor VIII bypassing activity/bypass activity

Explanation:
This is a guess, and the hits are mostly French, so there may be a better term, but it might get you on the right track.

http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=Pub...
"Factor VIII or factor IX replacement is frequently impossible in inhibitor-developing hemophiliacs, because of the level of the inhibitor titer... We performed a multicenter retrospective study to evaluate the use of FEIBA (Factor Eight Bypassing Activity) in France."

http://www.transfusionguidelines.org.uk/index.asp?Publicatio...
"FEIBA (factor VIII bypassing activity) concentrate"

In vivo bypass of hemophilia A coagulation defect by Factor XIIa ...These data verified that the increases in Factor VIII-bypass activity seemed to be positively correlated with decreases in Factor VII and concomitant ...
www.nature.com/nbt/journal/v18/n3/full/nbt0300_289.html

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Note added at 2 hrs (2007-07-25 12:22:06 GMT)
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http://www.hemophiliagalaxy.com/therapies/hemotherapies/feib...
There's an explanation of use of FEIBA in patients with factor VIII inhibitors here - maybe in your text "bypassante" is a nous, referring to the FEIBA product itself, so to paraphrase, in patients who have developed factor VIII inhibitors a FEIBA product can be used

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Note added at 2 hrs (2007-07-25 12:22:44 GMT)
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nous = noun

Selected response from:

Helen Genevier
France
Local time: 02:42

Grading comment

Thanks Helen...., my thanks also to Manu for his answer.
4 KudoZ points were awarded for this answer

Summary of answers provided

4 +1

bypassing or shunting

Drmanu49

2 +1

has factor VIII bypassing activity/bypass activity

Helen Genevier

Discussion entries: 2

Answers

3 mins confidence:

peer agreement (net): +1

bypassing or shunting

Explanation:
but not necessarily the way you understand it.

for example:

Inhibiteurs de Tyrosine Kinase (ITK), un concept et une ...... "bypassant" par là même la nécessité d'identifier. l'antigène tumoral. ...
www.institutpaolicalmettes.fr/pro/infoscient/rapport_scient...

La diminution d'amplitude de p.p.s.i. est accompagnée d'une réduction de shunt inhibiteur. Discussion des résultats en fonction des conclusions suivantes: ...
cat.inist.fr/?aModele=afficheN&cpsidt=9064075 -

Drmanu49
Local time: 02:42
Specializes in field
Native speaker of:

English,