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moucheté

English translation: speckled


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GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
French term or phrase:moucheté
English translation:speckled
Entered by: Helen Genevier
Options:
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18:04 Nov 18, 2011
French to English translations [PRO]
Medical - Medical: Health Care / patient reports MRI scan
French term or phrase: moucheté
Context:
'ANA positifs a 160 mouchetes M1[possibly Ml] avec auto-anticorps non specifiques d'organes negatifs de meme que les cryoglobulines.'
mportal
Local time: 17:14
speckled
Explanation:
It's an ANA (antinuclear antibodies) pattern.

"On décrit classiquement les aspects homogène, homogène à renforcement périphérique, moucheté et nucléolaire."
http://anne.decoster.free.fr/immuno/labomint/immmai.htm

"What is the significance of the ANA pattern?
[...]
Homogeneous - total nuclear fluorescence due to antibody directed against nucleoprotein. Common in SLE (lupus).
Peripheral - fluorescence occurs at edges of nucleus in a shaggy appearance. Anti-DNA antibodies cause this pattern. Also common in SLE (lupus).
Speckled - results from antibody directed against different nuclear antigens.
Nucleolar - results from antibody directed against a specific RNA configuration of the nucleolus or antibody specific for proteins necessary for maturation of nucleolar RNA. Seen in patients with systemic sclerosis."

http://arthritis.about.com/od/diagnostic/a/ana.htm
Selected response from:

Helen Genevier
France
Local time: 18:14
Grading comment
Thanks, Helen. This seemed unlikely, but your explanation is very helpful.
4 KudoZ points were awarded for this answer



Summary of answers provided
4 +3speckled
Helen Genevier


  

Answers


43 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +3
speckled


Explanation:
It's an ANA (antinuclear antibodies) pattern.

"On décrit classiquement les aspects homogène, homogène à renforcement périphérique, moucheté et nucléolaire."
http://anne.decoster.free.fr/immuno/labomint/immmai.htm

"What is the significance of the ANA pattern?
[...]
Homogeneous - total nuclear fluorescence due to antibody directed against nucleoprotein. Common in SLE (lupus).
Peripheral - fluorescence occurs at edges of nucleus in a shaggy appearance. Anti-DNA antibodies cause this pattern. Also common in SLE (lupus).
Speckled - results from antibody directed against different nuclear antigens.
Nucleolar - results from antibody directed against a specific RNA configuration of the nucleolus or antibody specific for proteins necessary for maturation of nucleolar RNA. Seen in patients with systemic sclerosis."

http://arthritis.about.com/od/diagnostic/a/ana.htm

Helen Genevier
France
Local time: 18:14
Native speaker of: Native in EnglishEnglish
PRO pts in category: 76
Grading comment
Thanks, Helen. This seemed unlikely, but your explanation is very helpful.

Peer comments on this answer (and responses from the answerer)
agree  1045
13 mins
  -> Thanks 1045 :-)

agree  Joanne Archambault
5 hrs
  -> Thanks Joanne :-)

agree  SJLD
12 hrs
  -> Thanks SJ :-)
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Changes made by editors
Nov 20, 2011 - Changes made by Helen Genevier:
Created KOG entryKudoZ term => KOG term
Nov 19, 2011 - Changes made by Emanuela Galdelli:
Term askedmouchete (acute on second e) => moucheté


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