This site uses cookies. Some of these cookies are essential to the operation of the site, while others help to improve your experience by providing insights into how the site is being used. For more information, please see the ProZ.com privacy policy.
Cookie settings
  1. KudoZ™ Top
  2. French to English
  3. Medical (general)

dose de charge

English translation: loading dose

13:20 Mar 13, 2004
French to English translations [PRO]
Medical - Medical (general) / IBS
French term or phrase: dose de charge
An initial dose given to reach a certain efficacy. Then I believe the dose is reduced/increased to maintain a certain level.
Pascale Dahan
United Kingdom
Local time: 09:04
English translation:loading dose
Explanation:
Domaine(s)
  – Posology
Domaine(s)
  – Posologie
 
loading dose Source
CORRECT

dose de mise en
charge Source CORRECT, FÉM

dose de charge Source
CORRECT, FÉM

DEF – Initial dose of a drug,
higher than that regularly
used, given with the objective
of rapidly providing an
effective drug concentration
Source

DEF – Forte dose initiale d'un
médicament administrée en
vue d'obtenir rapidement une
concentration efficace du
produit actif dans l'organisme.
Source


--------------------------------------------------
Note added at 2004-03-13 13:21:44 (GMT)
--------------------------------------------------

Termium
Selected response from:

GILLES MEUNIER
France
Local time: 10:04
Grading comment
Thank you.
4 KudoZ points were awarded for this answer



Summary of answers provided
3 +6loading dose
GILLES MEUNIER
4 +1initial dose
Hervé du Verle


  

Answers


1 min   confidence: Answerer confidence 3/5Answerer confidence 3/5 peer agreement (net): +6
loading dose


Explanation:
Domaine(s)
  – Posology
Domaine(s)
  – Posologie
 
loading dose Source
CORRECT

dose de mise en
charge Source CORRECT, FÉM

dose de charge Source
CORRECT, FÉM

DEF – Initial dose of a drug,
higher than that regularly
used, given with the objective
of rapidly providing an
effective drug concentration
Source

DEF – Forte dose initiale d'un
médicament administrée en
vue d'obtenir rapidement une
concentration efficace du
produit actif dans l'organisme.
Source


--------------------------------------------------
Note added at 2004-03-13 13:21:44 (GMT)
--------------------------------------------------

Termium

GILLES MEUNIER
France
Local time: 10:04
Native speaker of: French
PRO pts in category: 84
Grading comment
Thank you.

Peer comments on this answer (and responses from the answerer)
agree  chaac: A quantity higher than the average or maintenance dose, used at the initiation of therapy to rapidly establish a desired level of the drug in: http://www.dictionarybarn.com
4 mins
agree  Helen Genevier
5 mins
agree  Vicky Papaprodromou
6 mins
agree  Hacene
1 hr
agree  sktrans
2 hrs
agree  Josephine Billet: yes
5 hrs
Login to enter a peer comment (or grade)

44 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +1
initial dose


Explanation:
Usually studies indicate the "dose" of the initial dose. "Dose de charge" meaning a higher (or highest possible) initial dose is only seen in French

--------------------------------------------------
Note added at 7 hrs 18 mins (2004-03-13 20:38:41 GMT)
--------------------------------------------------

I made a quick search through the Medline database. A few US papers (mainly) used \"loading dose\" in clinical trials, often referring to short time trials (cardiac procedures for instance) and short term therapy; but a majority of papers speak of the initial dose (the first given to the patient at the beginning of the treatment) and of the subsequent doses. So...

Hervé du Verle
Local time: 04:04
Specializes in field
Native speaker of: Native in FrenchFrench
PRO pts in category: 148

Peer comments on this answer (and responses from the answerer)
agree  sktrans: ça correspond à la dose d'attaque, mais toutes les doses initiales ne sont pas d'attaque/de charge
1 hr
Login to enter a peer comment (or grade)



Login or register (free and only takes a few minutes) to participate in this question.

You will also have access to many other tools and opportunities designed for those who have language-related jobs (or are passionate about them). Participation is free and the site has a strict confidentiality policy.

Return to KudoZ list

KudoZ™ translation help

The KudoZ network provides a framework for translators and others to assist each other with translations or explanations of terms and short phrases.

See also:
ProZ.com term search
Search millions of term translations
Close search
Term search
  • All of ProZ.com
  • Term search
  • Jobs
  • Forums
  • Multiple search