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German: Bindetasche

English translation: binding site







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GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
German term or phrase:Bindetasche
English translation:binding site
Entered by:Ryan Orrock
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1:22pm Oct 8, 2007Login or register (free) for more options.
German to English translations [PRO]
Medical - Biology (-tech,-chem,micro-) / Proteins
German term or phrase: Bindetasche
Das Pfeil zeigt auf die Position der vermuteten Bindetasche für Flavonoide.

Is this simply receptor? Or is there a better term in EN?

Thanks!
Ryan Orrock
Germany
binding site / binding pocket
Explanation:
As, for example, in

http://ajplung.physiology.org/cgi/content/full/275/5/L902
"These data imply that the activation kinetics and the ***binding site(s) for flavonoids*** were significantly altered by forskolin stimulation." (and many more occurences)

http://www.plantcell.org/cgi/content/full/17/11/3141
"Figure 6. The Putative Acceptor ***Binding Pocket***.

Stereo diagram showing quercetin (A) and hederagenin (B) docked into the proposed ***binding pockets***. Quercetin, hederagenin, and UDP-glucose are shown as ball-and-stick models. Some protein residues in the acceptor ***binding pocket*** are labeled and shown in cyan as bond models. Distances (Å) between the OH group of acceptors and the atom NE2 of His-22 or the atom C1' of UDP-glucose are labeled and indicated with dashed lines."

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Note added at 35 mins (2007-10-08 13:58:19 GMT)
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occurences -> occurrences
Selected response from:

Steffen Walter
Germany
Note from asker to answerer
4 KudoZ points were awarded for this answer



Summary of answers provided
3 +2binding pocketDavid Hollywood
3 +2binding site / binding pocket
Steffen Walter


  

Answers

35 mins   confidence: Answerer confidence 3/5Answerer confidence 3/5 peer agreement (net): +2
binding site / binding pocket

Explanation:
As, for example, in

http://ajplung.physiology.org/cgi/content/full/275/5/L902
"These data imply that the activation kinetics and the ***binding site(s) for flavonoids*** were significantly altered by forskolin stimulation." (and many more occurences)

http://www.plantcell.org/cgi/content/full/17/11/3141
"Figure 6. The Putative Acceptor ***Binding Pocket***.

Stereo diagram showing quercetin (A) and hederagenin (B) docked into the proposed ***binding pockets***. Quercetin, hederagenin, and UDP-glucose are shown as ball-and-stick models. Some protein residues in the acceptor ***binding pocket*** are labeled and shown in cyan as bond models. Distances (Å) between the OH group of acceptors and the atom NE2 of His-22 or the atom C1' of UDP-glucose are labeled and indicated with dashed lines."

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Note added at 35 mins (2007-10-08 13:58:19 GMT)
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occurences -> occurrences

Steffen Walter
Germany
Works in field
Native speaker of: Native in GermanGerman
PRO pts in category: 12

Peer comments on this answer (and responses from the answerer)
agree Zareh Darakjian Ph.D.
19 mins

agree MMUlr
20 hrs
Login to enter a peer comment (or grade)


31 mins   confidence: Answerer confidence 3/5Answerer confidence 3/5 peer agreement (net): +2
binding pocket

Explanation:
File Format: PDF/Adobe Acrobat - View as HTML
In this contribution, we present an efficient method for comparing protein binding pockets. based on a spherical harmonics expansion. Binding pocket shapes ...
www.ebi.ac.uk/~rafi/docs/Morris_2005a.pdf - Similar pages

IngentaConnect Fast prediction and visualization of protein ...Fast prediction and visualization of protein binding pockets with PASS. Authors: Brady Jr. G.P.1; Stouten P.F.W.1. Source: Journal of Computer-Aided ...
www.ingentaconnect.com/content/klu/jcam/2000/00000014/00000... - Similar pages


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Note added at 33 mins (2007-10-08 13:55:40 GMT)
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We recently introduced Cavbase, a method for describing and comparing protein binding pockets on the basis of the geometrical and physicochemical properties ...
cat.inist.fr/?aModele=afficheN&cpsidt=17844401 - Similar pages

TITLE = {Analysis of protein binding pocket flexibility}, SCHOOL = {Universit{\"a}t des Saarlandes}, YEAR = {2004}, MONTH = {September}, ...
domino.mpi-inf.mpg.de/.../d3349db97ee34479c12565dd006fb8e1/03da2a8d113fc228c1256f4600474941!OpenDocument - 19k - Cached - Similar pages

A method for localizing ligand binding pockets in protein structures.A method for localizing ligand binding pockets in protein structures.
www.bio-computing.org/showabstract.php?pmid=16304646 - 20k - Cached - Similar pages


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Note added at 36 mins (2007-10-08 13:58:31 GMT)
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not my field but a lot of credible monolingual hits

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Note added at 38 mins (2007-10-08 14:01:03 GMT)
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This binding pocket contains 8 cysteine residues. A naturally occurring mutation affecting one of these cysteines is known to eliminate pRB's protein and ...
www.jbc.org/cgi/content/abstract/267/21/14846 - Similar pages

David Hollywood
Argentina
Native speaker of: Native in EnglishEnglish
PRO pts in category: 15

Peer comments on this answer (and responses from the answerer)
agree Zareh Darakjian Ph.D.: Yes. Binding site is much more common usage, though.
23 mins
  -> thanks Zareh and not my field as I say :)

agree MMUlr
20 hrs
Login to enter a peer comment (or grade)





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