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Kernzeichnung

English translation: nuclear staining


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18:48 Jan 2, 2010
German to English translations [PRO]
Science - Biology (-tech,-chem,micro-)
German term or phrase: Kernzeichnung
Autopsy report.
Histology of the heart.

Man erkennt verstärkt Verzweigung, Faserverbreiterung und Verlängerung der Myokardmyozyten. Die Kerne vergrößert, hyperchromatisch und bizarr gestaltet. Flächenhafte unregelmäßige begrenzte breite zell- und kapillararme faserreiche Narbe mit Verlust der Querstreifung und der Kernzeichnung.

Thanks!
lirka
Local time: 22:00
English translation:nuclear staining
Explanation:
I assume that "Kernzeichnung" means the same as "Kernfärbung" (but I'm not sure). There are quite a few hits in Google if you search for "heart histology" and "loss of nuclear staining". In some results, "cross-striation" (Querstreifung) is mentioned as well. Loss of nuclear staining seems to be an indication of cell death (karyolysis).
Selected response from:

SusanneM
Local time: 04:00
Grading comment
Thanks a lot. This is it, yes.
4 KudoZ points were awarded for this answer



Summary of answers provided
3 +4nuclear stainingSusanneM


Discussion entries: 1





  

Answers


1 hr   confidence: Answerer confidence 3/5Answerer confidence 3/5 peer agreement (net): +4
nuclear staining


Explanation:
I assume that "Kernzeichnung" means the same as "Kernfärbung" (but I'm not sure). There are quite a few hits in Google if you search for "heart histology" and "loss of nuclear staining". In some results, "cross-striation" (Querstreifung) is mentioned as well. Loss of nuclear staining seems to be an indication of cell death (karyolysis).


    Reference: http://books.google.com/books?id=sWL76bap44cC&printsec=front...
SusanneM
Local time: 04:00
Native speaker of: Native in GermanGerman
PRO pts in category: 4
Grading comment
Thanks a lot. This is it, yes.

Peer comments on this answer (and responses from the answerer)
agree  MMUlr: yes, IMO "loss of striation and nuclear staining (pattern)", i.e., DNA-positive staining reaction. see: http://eurheartj.oxfordjournals.org/cgi/reprint/26/17/1797 (find: "nuclear staining").
11 hrs
  -> Thank you, also for the link (there are many Google hits, but document access is often restricted).
agree  Anne Schulz
15 hrs
  -> Dankeschön.
agree  Dr Lofthouse
16 hrs
  -> Thank you.
agree  Harald Moelzer (medical-translator)
19 hrs
  -> Vielen Dank.
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Changes made by editors
Jan 2, 2010:
Kudoz queueIn queue => Public


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