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The asker opted for community grading. The question was closed on 2010-06-08 07:54:08 based on peer agreement (or, if there were too few peer comments, asker preference.)
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German to English translations [PRO]
Science - Biology (-tech,-chem,micro-) / microbiology | | German term or phrase: vielfach weitergeführtes Impfmaterial | Das so gewonnene und vielfach weitergeführte Impfmaterial erfährt einen hohen Grad an Organismenselektion und ist praktisch gleichzusetzen mit Starterkulturen.
Document about microbial cultures.
Looking for the sense of 'vielfach weitergeführt' |
|  mellterm.netKudoZ activityQuestions: 44 ( 2 open) ( 1 without valid answers) ( 3 closed without grading) Answers: 8
| Local time: 04:00
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| | vaccine/inoculum that has been passed a number of times | Explanation:
Modified live (attenuated) vaccines contain living bacterial or viral organisms. They are usually collected from a field disease and then grown in abnormal host cells (viral) or media (bacterial) to change or attenuate the pathogen. Each time the pathogen is grown through a replication, it is called a passage, and it is administered back to the animal to see if it can still cause disease. After several passages, the pathogen begins to lose virulence factors, since it cannot cause disease in these unnatural host cells. Once the pathogen can no longer cause disease in the target species, it is then tested to see if it can confer protection. The final vaccine is usually passed a number of times beyond the passage where virulence is no longer seen to decrease the risk of reversion to virulent pathogen.
http://www.thecattlesite.com/articles/1565/designing-vaccina...
...when an inoculum passed a small number of times in eggs was given by the intraperitoneal route in a 0.1 ml amount per bird.
http://shortify.com/Z29 |
| Selected response from:
casper
| Grading comment Hi Jennifer,
thanks! A model answer.
Simon
4 KudoZ points were awarded for this answer |
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| Discussion entries: 0 |
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Automatic update in 00:
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2 hrs confidence:   vaccine/inoculum that has been passed a number of times
Explanation:
Modified live (attenuated) vaccines contain living bacterial or viral organisms. They are usually collected from a field disease and then grown in abnormal host cells (viral) or media (bacterial) to change or attenuate the pathogen. Each time the pathogen is grown through a replication, it is called a passage, and it is administered back to the animal to see if it can still cause disease. After several passages, the pathogen begins to lose virulence factors, since it cannot cause disease in these unnatural host cells. Once the pathogen can no longer cause disease in the target species, it is then tested to see if it can confer protection. The final vaccine is usually passed a number of times beyond the passage where virulence is no longer seen to decrease the risk of reversion to virulent pathogen.
http://www.thecattlesite.com/articles/1565/designing-vaccina...
...when an inoculum passed a small number of times in eggs was given by the intraperitoneal route in a 0.1 ml amount per bird.
http://shortify.com/Z29
| casper
Native speaker of:  English
PRO pts in category: 12
|
| | Grading comment Hi Jennifer,
thanks! A model answer.
Simon |
| | Login to enter a peer comment (or grade) |
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| Changes made by editors |
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| Jun 6, 2010 - Changes made by Gudrun Dauner: | | Term asked | vielfach weitergeführte Impfmaterial => vielfach weitergeführtes Impfmaterial |
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The translation workplace 
