Überschreitung der inneren gruppensequentiellen Stoppgrenzen

08:22 Aug 29, 2008 

One, you may well be doing a re-translation. Two, there may be a more stat-speak term for Stoppgrenze, such as Annahmegrenze, which could be acceptance line, or Klassengrenze (class limit). Check with author?

12:24 Aug 28, 2008 

The text is a Methologische Stellungnahme (by a biometrist)
The question deals with the design of the study:
Die Power von 80% lässt es immerhin zu, dass ein Unterschied im relativen Risiko 2 mit einer Wahrscheinlichkeit von 20% "unentdeckt" bleibt. Dies gilt insbesondere auch dann, wenn die Studie abgebrochen wird, wenn die inneren gruppensequentiellen Stoppgrenzen überschritten werden. Entsprechend findet der biometrische Gutachter die folgende Aussage auf S. 42 des Studienprotokolls als irreführend: "If the test statistic is between the inner-wedge boundaries, then an alternative hypothesis of RR equal to 2.0 can be safely claimed untrue, and the study management may consider stopping the study for futility".
I would add that I suspect the German text is a translation from English already.
Thanks for your help.
Antoinette

08:11 Aug 28, 2008 

As Chetan says, Antoinette, it's absolutely impossible for us to know what it's a case of without seeing a larger chunk of the text. Also, what other references to this term are there in other parts of the document?

03:59 Aug 28, 2008 

Am sure KudoZ-ians would be equally happy to have more context :-) Please (always and at least) provide the source sentence/para. Thanks.