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DCMi

English translation: inflammatory dilated cardiomyopathy (DCMI)

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GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
German term or phrase:inflammatorische dilatative Kardiomyopathie (DCMi)
English translation:inflammatory dilated cardiomyopathy (DCMI)
Entered by: Steffen Walter
Options:
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21:20 Jul 6, 2008
German to English translations [PRO]
Medical - Medical: Cardiology / autoreactive conditions
German term or phrase: DCMi
Die Bewertung der bisherigen Studien ergibt somit ein uneinheitliches Bild, maximal einen Evidenzgrad C, Indikation IIb. Für Patienten mit einer Myokarditis und bioptisch ausgeschlossener Viruspersistenz liegen bisher überhaupt keine randomisierten Studien vor. Deshalb sollte eine immunsuppressive Therapie bei autoreaktiver **DCMi** nach Ausschluß einer Viruspersistenz im Myokard gegenwärtig nur in einer doppelt blinden randomisierten Studie oder in Follow-up-Registern erfolgen. Diese Empfehlung trifft auch für die Behandlung viraler Kardiomyopathien (mit oder ohne Inflammation) durch Interferon zu.

I checked the glossaries, but could not find this...
Any help?

Thank you.
Zareh Darakjian Ph.D.
United States
Local time: 01:32
inflammatory dilated cardiomyopathy
Explanation:
see:
http://www.medizinische-abkuerzungen.de/


What are the types of cardiomyopathy?

There are three major types of cardiomyopathy – dilated cardiomyopathy, hypertrophic cardiomyopathy, and restrictive cardiomyopathy. The vast majority of patients who develop cardiomyopathy have the dilated form. So, after briefly describing hypertrophic and restrictive cardiomyopathies, we will concentrate on dilated cardiomyopathy for the remainder of this article.

In dilated cardiomyopathy (often referred to as congestive cardiomyopathy or congestive heart failure), previously normal heart muscle becomes damaged, leading to a generalized weakening of the walls of the cardiac chambers. To compensate for the weakening of their muscular walls, the cardiac chambers dilate. (The dilation of the cardiac chambers, especially of the left ventricle, is often referred to as "remodeling.") The weakening and the dilation of the heart muscle eventually lead to heart failure.

What causes dilated cardiomyopathy?

... Another common cause of dilated cardiomyopathy is inflammation of the heart muscle, a condition called myocarditis. Myocarditis is most often caused by viral infections, but can also be caused by bacterial infections and by non-infectious causes such as lupus and other inflammatory diseases.

http://heartdisease.about.com/cs/heartfailure/a/CHF1.htm


Myocarditis and dilated cardiomyopathy: An inflammatory link

Jay W Mason*
Department of Internal Medicine, J527 Kentucky Clinic 0284, University of Kentucky, Lexington, KY 40506, USA

Myocarditis is, by definition, an inflammatory disorder, while dilated cardiomyopathy (DCM) is, in most cases, idiopathic. However, accumulating data has revealed an important inflammatory component in the pathogenesis of DCM, and there is growing evidence that myocarditis and DCM are closely related. The purpose of this review is to demonstrate the interrelationship between the two. This topic was authoritatively reviewed in 1999 by Kawai [1]. By examining the pathogenesis of myocarditis we will consider mechanisms by which viral myocarditis might cause dilated cardiomyopathy. We will then review the basic and clinical evidence supporting the claim that myocarditis is a common precursor of DCM.
http://cardiovascres.oxfordjournals.org/cgi/content/full/60/...
Selected response from:

Patricia Daehler
United States
Local time: 04:32
Grading comment
Thank you, Dr. Daehler.
Thank you Dr. Raptis and Jeannette.
4 KudoZ points were awarded for this answer

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Summary of answers provided
3 +2inflammatory dilated cardiomyopathy
Patricia Daehler


  

Answers


43 mins   confidence: Answerer confidence 3/5Answerer confidence 3/5 peer agreement (net): +2
inflammatory dilated cardiomyopathy


Explanation:
see:
http://www.medizinische-abkuerzungen.de/


What are the types of cardiomyopathy?

There are three major types of cardiomyopathy – dilated cardiomyopathy, hypertrophic cardiomyopathy, and restrictive cardiomyopathy. The vast majority of patients who develop cardiomyopathy have the dilated form. So, after briefly describing hypertrophic and restrictive cardiomyopathies, we will concentrate on dilated cardiomyopathy for the remainder of this article.

In dilated cardiomyopathy (often referred to as congestive cardiomyopathy or congestive heart failure), previously normal heart muscle becomes damaged, leading to a generalized weakening of the walls of the cardiac chambers. To compensate for the weakening of their muscular walls, the cardiac chambers dilate. (The dilation of the cardiac chambers, especially of the left ventricle, is often referred to as "remodeling.") The weakening and the dilation of the heart muscle eventually lead to heart failure.

What causes dilated cardiomyopathy?

... Another common cause of dilated cardiomyopathy is inflammation of the heart muscle, a condition called myocarditis. Myocarditis is most often caused by viral infections, but can also be caused by bacterial infections and by non-infectious causes such as lupus and other inflammatory diseases.

http://heartdisease.about.com/cs/heartfailure/a/CHF1.htm


Myocarditis and dilated cardiomyopathy: An inflammatory link

Jay W Mason*
Department of Internal Medicine, J527 Kentucky Clinic 0284, University of Kentucky, Lexington, KY 40506, USA

Myocarditis is, by definition, an inflammatory disorder, while dilated cardiomyopathy (DCM) is, in most cases, idiopathic. However, accumulating data has revealed an important inflammatory component in the pathogenesis of DCM, and there is growing evidence that myocarditis and DCM are closely related. The purpose of this review is to demonstrate the interrelationship between the two. This topic was authoritatively reviewed in 1999 by Kawai [1]. By examining the pathogenesis of myocarditis we will consider mechanisms by which viral myocarditis might cause dilated cardiomyopathy. We will then review the basic and clinical evidence supporting the claim that myocarditis is a common precursor of DCM.
http://cardiovascres.oxfordjournals.org/cgi/content/full/60/...


Patricia Daehler
United States
Local time: 04:32
Specializes in field
Native speaker of: Native in GermanGerman
PRO pts in category: 68
Grading comment
Thank you, Dr. Daehler.
Thank you Dr. Raptis and Jeannette.
Notes to answerer
Asker: Thank you, Dr. Daehler for your taking the time... and for this detailed explanation and references.


Peer comments on this answer (and responses from the answerer)
agree  raptisi
10 hrs
  -> Thank you raptisi

agree  Jeannette Lakèl
11 hrs
  -> Thank you Jeannette
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Changes made by editors
Jul 21, 2008 - Changes made by Steffen Walter:
Edited KOG entry<a href="/profile/34047">Steffen Walter's</a> old entry - "inflammatorische dilatative Kardiomyopathie (DCMi)" » "inflammatory dilated cardiomyopathy"
Jul 21, 2008 - Changes made by Steffen Walter:
Edited KOG entry<a href="/profile/116303">Patricia Daehler's</a> old entry - "DCMi" » "inflammatory dilated cardiomyopathy"
Jul 7, 2008 - Changes made by Patricia Daehler:
Created KOG entryKudoZ term » KOG term
Jul 7, 2008 - Changes made by Patricia Daehler:
Edited KOG entry<a href="/profile/116303">Patricia Daehler's</a> old entry - "DCMi" » "inflammatory dilated cardiomyopathy"
Jul 7, 2008 - Changes made by Steffen Walter:
Field (write-in)autoreactive conditions... » autoreactive conditions


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