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Faktor V-Leiden-Mutation

English translation: Factor V Leiden

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GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
German term or phrase:Faktor V-Leiden-Mutation
English translation:Factor V Leiden
Entered by: Jonathan MacKerron
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08:26 Apr 4, 2007
German to English translations [PRO]
Medical - Medical: Pharmaceuticals / OCs
German term or phrase: Faktor V-Leiden-Mutation
"...Tests zur APC-Resistenz (Faktor V-Leiden-Mutation)...", no other context to provide I'm afraid - thanks in advance
Jonathan MacKerron
FV R506Q
Explanation:
Resistance to activated protein C due to Factor V R506Q (Factor V Leiden)...Using the single letter amino-acid code the mutant FV can therefore be written as FV R506Q but is more often referred to as FV Leiden (Figure 1)
http://www.jr2.ox.ac.uk/bandolier/bandopubs/keeling.html

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Note added at 47 mins (2007-04-04 09:14:52 GMT)
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The factor V Leiden (FVL) mutation is the most common genetic risk factor for thrombosis and accounts for more than 90% of patients with APC resistance
http://www.arupconsult.com/Topics/Hematologic_Disease/Thromb...
Selected response from:

casper
Grading comment
I went with Factor V Leiden, thanks to all
4 KudoZ points were awarded for this answer

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Summary of answers provided
3 +2FV R506Qcasper


  

Answers


45 mins   confidence: Answerer confidence 3/5Answerer confidence 3/5 peer agreement (net): +2
FV R506Q


Explanation:
Resistance to activated protein C due to Factor V R506Q (Factor V Leiden)...Using the single letter amino-acid code the mutant FV can therefore be written as FV R506Q but is more often referred to as FV Leiden (Figure 1)
http://www.jr2.ox.ac.uk/bandolier/bandopubs/keeling.html

--------------------------------------------------
Note added at 47 mins (2007-04-04 09:14:52 GMT)
--------------------------------------------------

The factor V Leiden (FVL) mutation is the most common genetic risk factor for thrombosis and accounts for more than 90% of patients with APC resistance
http://www.arupconsult.com/Topics/Hematologic_Disease/Thromb...

casper
Native speaker of: Native in EnglishEnglish
PRO pts in category: 98
Grading comment
I went with Factor V Leiden, thanks to all

Peer comments on this answer (and responses from the answerer)
neutral  Dirgis: I would rather use factor V Leiden
3 hrs
  -> I agree with you, Sigrid. Please see the text quoted from the first web reference above

agree  Cetacea: with "factor V Leiden mutation".
6 hrs
  -> Thanks, Cetacea

agree  Gisela Greenlee: with factor V Leiden mutation also
9 hrs
  -> Thank you, giselrike, for confirming this
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