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faktorsavó

English translation: serum factor

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GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
Hungarian term or phrase:faktorsavó
English translation:serum factor
Entered by: Katalin Szilárd
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09:01 May 23, 2003
Hungarian to English translations [PRO]
Medical - Biology (-tech,-chem,micro-) / Microbiology
Hungarian term or phrase: faktorsavó
"a biokémiai identifikálás elhagyható, amennyiben a szerológiai vizsgálat során használt faktorsavókkal kifogástalan differenciálást érünk el."
Andrea Vermesi
Local time: 00:00
serum factor
Explanation:
Rheumatoid Factors are immunoglobulins of any isotype with antibody activity directed against antigenic sites on the Fc region of human or animal immunoglobulin G (IgG). After the discovery by Waaler 1 and the independent rediscovery by Rose and co-workers 2 that the sera from patients with rheumatoid arthritis agglutinated sheep erythrocytes coated with rabbit anti-sheep erythrocyte antibody, it was determined that the serum factor responsible for the agglutination was a high-molecular immunoglobulin of the IgM class. IgM-RF is the main isotype identified by clinically available diagnostic assays for RF detection. Assays for RF are the most widely used serological tests as an aid for the diagnosis of rheumatoid arthritis (RA).1,2

"Type beta transforming growth factor is the primary differentiation-inducing serum factor for normal human bronchial epithelial cells"

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Katalin Szilárd
Hungary
Local time: 00:00
Grading comment
4 KudoZ points were awarded for this answer

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Summary of answers provided
4 +2serum factor
Katalin Szilárd


  

Answers


1 hr   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +2
serum factor


Explanation:
Rheumatoid Factors are immunoglobulins of any isotype with antibody activity directed against antigenic sites on the Fc region of human or animal immunoglobulin G (IgG). After the discovery by Waaler 1 and the independent rediscovery by Rose and co-workers 2 that the sera from patients with rheumatoid arthritis agglutinated sheep erythrocytes coated with rabbit anti-sheep erythrocyte antibody, it was determined that the serum factor responsible for the agglutination was a high-molecular immunoglobulin of the IgM class. IgM-RF is the main isotype identified by clinically available diagnostic assays for RF detection. Assays for RF are the most widely used serological tests as an aid for the diagnosis of rheumatoid arthritis (RA).1,2

"Type beta transforming growth factor is the primary differentiation-inducing serum factor for normal human bronchial epithelial cells"




    Reference: http://www.fda.gov/cdrh/ode/rhuema.html
    Reference: http://cellbank.nihs.go.jp/information/research/jcrbpublicat...
Katalin Szilárd
Hungary
Local time: 00:00
Works in field
Native speaker of: Native in HungarianHungarian
PRO pts in category: 17

Peer comments on this answer (and responses from the answerer)
agree  xxxdenny
1 hr

agree  Daniela Ballif
4 hrs
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