Italian to English translations [PRO]
Medical - Medical: Pharmaceuticals / clinical study statistics | | Italian term or phrase: prima ipotesi alternativa | This is from a study design document.
"La prima ipotesi alternativa principale è che la percentuale di responder (pazienti con riduzione della frequenza degli accessi 2:50%) nei pazienti trattati con Eslicarbazepina Acetato nel corso del periodo di mantenimento, sia differente da quella dei pazienti trattati con placebo"
I'm sure there's a standard phrase for this but I can't seem to remember it at the moment.
Anyone use this regularly? |
|   Alexander ChisholmKudoZ activityQuestions: 3058 (none open) ( 21 without valid answers) ( 9 closed without grading) Answers: 197
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| | (primary) alternative hypothesis | Explanation:
The primary is sometimes optional.
http://en.wikipedia.org/wiki/Multiregional_origin_of_modern_...
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Note added at 15 mins (2012-01-09 07:39:40 GMT)
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http://changingminds.org/explanations/research/initiation/hy...
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Note added at 16 mins (2012-01-09 07:40:45 GMT)
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Primary hypothesis
The **primary (or alternative) hypothesis** (or just the first in a long list) is often written as H1.
Experiments often seek to prove the primary hypothesis to be true and may be considered to have 'failed' if this is not achieved. In reality, an experiment succeeds when it correctly concludes that the primary hypothesis is true or false. It only fails when its conclusions are incorrect (or that a correct conclusion is incorrectly reached).
Null hypothesis
The null hypothesis (often written as H0) is the opposite of the primary hypothesis in that it includes all other outcomes.
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Note added at 18 mins (2012-01-09 07:43:02 GMT)
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http://health.bsd.uchicago.edu/filestore/Biostatlab/phase2tr...
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Note added at 19 mins (2012-01-09 07:44:20 GMT)
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A brief description of the algorithm:
### 1. Come up with H0, and several alternative hypotheses.
### 2. Determine total sample size (n) based on the response-only H0 and the
### ** primary alternative hypothesis (A)** using Simon's 2-stage design (n=50
### in the example used in the paper).
### 3. Search over plausible stage 1 sizes (we searched n1=17...25, which is
### between 1/3 and 1/2 of the total sample size).
### 4. For each n1, search over the stopping rules under H0, and find designs
### with the desired alpha rate. |
| Selected response from:
Zareh Darakjian Ph.D.
Local time: 20:48
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The translation workplace 
