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GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
Romanian term or phrase:
amidonglicolat de sodiu (amidonoglicolat de sodiu)
Explanation: In cazul in care este vorba despre glicolat si nu gluconat... :)
Sodium Starch Glycolate
1] Description: Sodium salt of carboxymethyl ether of starch. White to off-white, tasteless, odorless, relatively free flowing powder. Practically insoluble in organic solvents.
Absorbs water rapidly, resulting in swelling which leads to rapid disintegration of tablets and granules.
2] Physical Characteristics: VivastarÒ Type
Viscosity
(2% solution) mPa s
*P
Non-viscous
P 0100
< 800
P 1000
< 2000
P 1500
> 1500
P 3500
> 2000
< 5000
P 5000
> 5000
* P refers potato starch origin. Also available from corn, wheat, and rice origins.
3] Applications:
Disintegrant dissolution aid for tablets, capsules and pellets
Recommended concentration: 1.0 – 4.0%. May need to use up to 6.0% In wet granulation formulations, normally effective intragranularly. However, may be more effective if added 50% intragranularly, and 50% extra-granularly (in the final dry mixture).
Explotab and VivastarP, for direct compression
Explotab CLV, for use intragranularly
Explotab Low pH, for use with actives susceptible to high pH
Explotab V17, provides enhanced swelling
Vivastar (PFS), Solvent Free
Suspending agent
Gelling agent VivastarÒ comes in a wide variety of types which can be used with water to produce translucent suspensions or clear gels over a wide viscosity range.
dar trebuie sa intrebi... personal, eu nu am auzit de glocolat, dar nici nu sunt atotstiutoare... asa ca intreaba intai un farmacist ceva si daca zice ca e chiar glocolat nu pot sa te ajut pentru ca nu cunosc termenul.. sorry!:)
-------------------------------------------------- Note added at 8 mins (2009-05-26 13:21:55 GMT) --------------------------------------------------
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... fruit), L-5-Hydroxytrytophan, Co-Enzyme B-12 (Dibencozide). Other Ingredients: Microrystalline Cellulose, Dextrose, LActose Monohydrate, Sodium Starch Gluconate, Magensium Stearate, Stearic ...
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-------------------------------------------------- Note added at 9 mins (2009-05-26 13:23:30 GMT) --------------------------------------------------
TABLE A Microencapsulation of Carprofen BATCH FORMULA Ingredient Weight (grams) % Carprofen (Pharmaceutical) 7.580 18.95% Ethycellulose (30 gm of 4% ethanol 1.200 3.00% solution) Sodium starch gluconate 31.220 78.05% Totals 40 100.00% http://www.patentstorm.us/patents/6541025/description.html
-------------------------------------------------- Note added at 10 mins (2009-05-26 13:24:35 GMT) --------------------------------------------------