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modificaciones en el tránsito del CFTR a la membrana

English translation: alteration/modification/defective CFTR transport


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11:12 Apr 7, 2011
Spanish to English translations [PRO]
Biology (-tech,-chem,micro-)
Spanish term or phrase: modificaciones en el tránsito del CFTR a la membrana
Se trata de una tesis sobre fibrosis quísitica. En una de sus partes dice lo siguiente:
Una consecuencia de la falta de regulación de la endocitosis y la exocitosis en células FQ y la falata de acidificación suficiente en sus organelas puede ser la existencia de posibles fallas en las modificaciones post-traduccionales y en el tránsito del CFTR a la membrana.
Mi duda es con relación a "el tránsito del CFTR a la membrana". Es correcto si lo traduzco como CFTR traffic to the membrane?
Muchas gracias!
Karina Rodriguez
Local time: 02:11
English translation:alteration/modification/defective CFTR transport
Explanation:
CFTR is affected =>modificaciones en el transito. therefore the passage of Cl ions is also affected

http://www.cell.com/retrieve/pii/0092867490901488

http://mcb.berkeley.edu/labs/machen/images/phmodel.jpg
Selected response from:

Lourdes Sanchez
Local time: 01:11
Grading comment
gracias!
4 KudoZ points were awarded for this answer



Summary of answers provided
5 +1alteration/modification/defective CFTR transportLourdes Sanchez
4 +1and the transport of CFTR to the membrane
James A. Walsh
5CFTR (Cystic fibrosis transmembrane conductance regulator)
Carmen Gabás


  

Answers


23 mins   confidence: Answerer confidence 5/5
CFTR (Cystic fibrosis transmembrane conductance regulator)


Explanation:
Si, es el mismo termino


    Reference: http://en.wikipedia.org/wiki/Cystic_fibrosis_transmembrane_c...
Carmen Gabás
United Kingdom
Local time: 06:11
Specializes in field
Native speaker of: Native in SpanishSpanish
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26 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +1
y el tránsito del CFTR a la membrana
and the transport of CFTR to the membrane


Explanation:
CFTR is:

Cystic fibrosis transmembrane conductance regulator, a protein involved in the transport of chloride ions across cell membranes

See reference link below.


    Reference: http://en.wikipedia.org/wiki/Cystic_fibrosis_transmembrane_c...
James A. Walsh
Spain
Local time: 07:11
Works in field
Native speaker of: Native in EnglishEnglish, Native in SpanishSpanish

Peer comments on this answer (and responses from the answerer)
agree  fvasconcellos
12 mins
  -> Thank you.
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3 hrs   confidence: Answerer confidence 5/5 peer agreement (net): +1
alteration/modification/defective CFTR transport


Explanation:
CFTR is affected =>modificaciones en el transito. therefore the passage of Cl ions is also affected

http://www.cell.com/retrieve/pii/0092867490901488

http://mcb.berkeley.edu/labs/machen/images/phmodel.jpg

Lourdes Sanchez
Local time: 01:11
Specializes in field
Native speaker of: Spanish
PRO pts in category: 8
Grading comment
gracias!

Peer comments on this answer (and responses from the answerer)
agree  Muriel Vasconcellos
15 hrs
  -> thank you
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