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refractaría

English translation: refractory to


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GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
Spanish term or phrase:refractaría
English translation:refractory to
Options:
- Contribute to this entry
- Include in personal glossary

23:36 Jul 9, 2009
    The asker opted for community grading. The question was closed on 2009-07-13 00:54:04 based on peer agreement (or, if there were too few peer comments, asker preference.)


Spanish to English translations [PRO]
Medical - Medical: Health Care
Spanish term or phrase: refractaría
paciente ***refractaria*** a anti-TNF y MTX
Suzanne Couture
United States
Local time: 09:17
refractory to
Explanation:
Hope this helps!



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Note added at 3 mins (2009-07-09 23:40:30 GMT)
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http://dictionary.reference.com/browse/refractory

2. resisting ordinary methods of treatment.


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Note added at 6 mins (2009-07-09 23:43:28 GMT)
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http://www.ingentaconnect.com/content/els/07507658/2003/0000...

http://www.bloodline.net/articles/blr_1_1_witzig.html

About the same time as the study just discussed, another study was conducted to approach the question of whether yttrium was adding anything to standard therapy. This study took patients who had undergone Rituxan therapy but had failed it. Failure of Rituxan therapy was defined in two ways: a patient responded, but the response lasted less than six months, or a patient was simply refractory to the therapy.

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Note added at 8 mins (2009-07-09 23:45:17 GMT)
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http://gateway.nlm.nih.gov/MeetingAbstracts/ma?f=102246753.h...

Disseminated infection caused by Blastoschizomyces capitatus is frequently fatal in granulocytopenic patients, despite the administration of Amphotericin B. The cause of this refractoriness is not known. We study four isolates of B. capitatus isolated from granulocytopenic patients with disseminated blastoschizomycosis that were refractory to Amphotericin B. Materials andMETHODS: MICs of Amphotericin B were determined by using the standard microdilution method approved by NCCLS. Two different inocula ...

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Note added at 3 days1 hr (2009-07-13 01:13:07 GMT) Post-grading
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Many thanks to all!!
Selected response from:

MariaMast
Local time: 02:17
Grading comment
Selected automatically based on peer agreement.
4 KudoZ points were awarded for this answer



Summary of answers provided
4 +5refractory to
MariaMast
4 +4resistant to
Richard McDorman
5lack of response/unresponsiveDavid Brown
Summary of reference entries provided
liz askew

Discussion entries: 3





  

Answers


15 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +4
resistant to


Explanation:
Note: The original text does not appear to have an accent over the i. I think that the word in the original is therefore "refractaria", and not "refractaría." This seems to make more sense, given the context.

re·frac·ta·rio -ria

adj.
(1) [physics] refractory, heat-resistant
(2) [figurative] (opuesto) refractory, resistant

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Note added at 16 mins (2009-07-09 23:53:01 GMT)
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http://education.yahoo.com/reference/dict_en_es/spanish/refr...

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Note added at 19 mins (2009-07-09 23:55:34 GMT)
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Note: Perhaps you can check the original carefully, to see if the word ending is -ia or -ía, as there is a discrepancy between the way the word appears in the question and in the context sentence you provided.

Richard McDorman
United States
Local time: 10:17
Native speaker of: Native in EnglishEnglish

Peer comments on this answer (and responses from the answerer)
agree  pitranslation: I agree with Richard
25 mins
  -> Thank you very much! :)

agree  Vertigirl: That's how I use it.
1 hr
  -> Thank you.

agree  Gabriela Mejías: That's how I use it too. Saludos, Richard. :)
2 hrs
  -> Thanks, Gabriela.

agree  Anandrade
19 hrs
  -> Thank you.
Login to enter a peer comment (or grade)

6 hrs   confidence: Answerer confidence 5/5
lack of response/unresponsive


Explanation:
Although "refractory" is commonly used in English. "Resistant" is too strong a word to use in this case

A definition of "refractorio/a"- Relativo a la falta de respuesta de una enfermedad a un determinado tratamiento

David Brown
Local time: 16:17
Specializes in field
Native speaker of: Native in EnglishEnglish
PRO pts in category: 105
Login to enter a peer comment (or grade)

3 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +5
refractory to


Explanation:
Hope this helps!



--------------------------------------------------
Note added at 3 mins (2009-07-09 23:40:30 GMT)
--------------------------------------------------

http://dictionary.reference.com/browse/refractory

2. resisting ordinary methods of treatment.


--------------------------------------------------
Note added at 6 mins (2009-07-09 23:43:28 GMT)
--------------------------------------------------

http://www.ingentaconnect.com/content/els/07507658/2003/0000...

http://www.bloodline.net/articles/blr_1_1_witzig.html

About the same time as the study just discussed, another study was conducted to approach the question of whether yttrium was adding anything to standard therapy. This study took patients who had undergone Rituxan therapy but had failed it. Failure of Rituxan therapy was defined in two ways: a patient responded, but the response lasted less than six months, or a patient was simply refractory to the therapy.

--------------------------------------------------
Note added at 8 mins (2009-07-09 23:45:17 GMT)
--------------------------------------------------

http://gateway.nlm.nih.gov/MeetingAbstracts/ma?f=102246753.h...

Disseminated infection caused by Blastoschizomyces capitatus is frequently fatal in granulocytopenic patients, despite the administration of Amphotericin B. The cause of this refractoriness is not known. We study four isolates of B. capitatus isolated from granulocytopenic patients with disseminated blastoschizomycosis that were refractory to Amphotericin B. Materials andMETHODS: MICs of Amphotericin B were determined by using the standard microdilution method approved by NCCLS. Two different inocula ...

--------------------------------------------------
Note added at 3 days1 hr (2009-07-13 01:13:07 GMT) Post-grading
--------------------------------------------------

Many thanks to all!!

MariaMast
Local time: 02:17
Specializes in field
Native speaker of: Native in SpanishSpanish
PRO pts in category: 8
Grading comment
Selected automatically based on peer agreement.

Peer comments on this answer (and responses from the answerer)
agree  Denise Southern: refractaria/o without accent in Spanish
1 hr
  -> Thank you very much Denise :)

agree  ARS54: ...Es eso, :) See: http://www.google.it/search?hl=it&q="patients refractory to"... *Resistant* is a slightly different concept. Anna Rosa
2 hrs
  -> Thank you very much ARS54

agree  Panagiotis Andrias: Agree with AR. See...OS and PFS did not differ significantly between platinum-resistant and platinum-refractory disease (p = 0.799 and p = 0.322 respectively) or according to ... linkinghub.elsevier.com/retrieve/pii/S0090825806007141 -
8 hrs
  -> Thank you very much Panagiotis :)

agree  liz askew: http://209.85.229.132/search?q=cache:bpy-ABrXauUJ:www.proz.c...
9 hrs
  -> Thank you very much liz:)

agree  Susana Sherman
17 hrs
  -> Thank you very much Susana :)
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Reference comments


9 hrs
Reference

Reference information:
English term or phrase: MTX-refractory
Spanish translation: refractaria al metotrexate
Entered by: Cecilia Palluzzi
Options:
- Contribute to this entry

18:28 Jan 18, 2006 Login or register (free) for more options.
English to Spanish translations [PRO]
Medical - Medical: Pharmaceuticals / Rheumatology
English term or phrase: MTX-refractory
Complete sentence: Inhibition of structural damage at 2 years in MTX-refractory established RA.
Son datos de un estudio sobre la aplicxacion de cierto medicamento en el tratamiento de AR.
También necesito corroborar el uso de naive en "MTX-naive".
Gracias!!!
Cecilia Palluzzi
Argentina

Local time: 02:43
refractaria al metotrexate
Explanation:
Methotrexate is a disease-modifying anti-rheumatic drug (DMARD). MTX-naive is a patient who has never used methotrexate

liz askew
United Kingdom
Specializes in field
Native speaker of: Native in EnglishEnglish
PRO pts in category: 348
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