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Spanish: A esta dosis tóxica para la maternidad

English translation: at this toxic dose during gestation/pregnancy







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GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
Spanish term or phrase:A esta dosis tóxica para la maternidad
English translation:at this toxic dose during gestation/pregnancy
Entered by:Adam Burman
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9:09pm Nov 7, 2006Login or register (free) for more options.
Spanish to English translations [PRO]
Medical - Medical: Pharmaceuticals / Investigator\'s brochure
Spanish term or phrase: A esta dosis tóxica para la maternidad
Referring to the effects on rats of a novel antidepressant (SSRI)

In a perinatal/postnatal toxicity study, a 300 mg/Kg/day dose was associated with a reduction in gestational body weight gain, a decrease in food consumption during pregnancy and a slight increase in the duration of gestation.

A esta dosis tóxica para la maternidad, también se observó un descenso del peso de la cría al nacer y una disminución de la viabilidad de la cría hasta el día 4 inclusive.

... a decrease in the weight of the litter at birth and a decrease in the viability of the litter up to day 4 inclusive were also observed.

TIA
Adam Burman
United Kingdom
at this toxic dose during gestation/pregnancy
Explanation:
-
Selected response from:

Hervé du Verle
United Kingdom
Note from asker to answerer
Thanks Hervé!
4 KudoZ points were awarded for this answer



Summary of answers provided
4 +2at this toxic dose during gestation/pregnancy
Hervé du Verle
5At this maternally toxic dose
Daniel Coria
3 +2at a dosage level which proves toxic during pregnancyxxxmuitoprazer


  

Answers

8 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +2
at this toxic dose during gestation/pregnancy

Explanation:
-

Hervé du Verle
United Kingdom
Specializes in field
Native speaker of: Native in FrenchFrench
PRO pts in category: 4
Note from asker to answerer
Thanks Hervé!

Peer comments on this answer (and responses from the answerer)
agree Annissa 7ar
14 hrs

agree Rondina
34 days
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3 mins   confidence: Answerer confidence 3/5Answerer confidence 3/5 peer agreement (net): +2
at a dosage level which proves toxic during pregnancy

Explanation:
is how I would frame this in relation to this

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Note added at 10 mins (2006-11-07 21:19:42 GMT)
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it was further observed that there was......then add your sentence!

xxxmuitoprazer
United Kingdom
Native speaker of: Native in EnglishEnglish

Peer comments on this answer (and responses from the answerer)
agree Zareh Darakjian Ph.D.: lI think this is good..
1 min
  -> thanx-but maybe not toxic during normal state when rat's hormones are more regular is the implication.

agree VRN
13 mins
  -> thanx
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26 mins   confidence: Answerer confidence 5/5
At this maternally toxic dose

Explanation:
876. Abamectin (addendum) (Pesticide residues in food: 1994 ...
A marked increase in the incidence of cleft palates, which exceeded the range seen in historical controls, was observed at this maternally toxic dose. ...
www.inchem.org/documents/jmpr/jmpmono/v94pr02.htm

NTP: Abstract for Teratology: Glyoxal Trimeric Dihydrate
If notable developmental effects had been observed at this maternally toxic dose, lower doses would have been tested. Animals were observed daily for ...
http://ntp-server.niehs.nih.gov/index.cfm?objectid=0730DDAC-...

[PDF] Proposed Regulatory Decision Document
File Format: PDF/Adobe Acrobat - View as HTML
reduced body-weight gains, litter loss and clinical signs of toxicity. Pups were found to. have minor skeletal variations at this maternally toxic dose. ...
http://www.pmra-arla.gc.ca/english/pdf/prdd/prdd2005-04-e.pd...

[DOC] Report all. [master]
File Format: Microsoft Word
An increase in separated origins of the carotid arteries indicated potential teratogenicity at this maternally toxic dose. Vinclozolin has been tested for ...
http://www.fao.org/WAICENT/FAOINFO/AGRICULT/AGP/AGPP/Pestici...

Hope it helps!

Daniel Coria
Argentina
Native speaker of: Native in SpanishSpanish
PRO pts in category: 16

Peer comments on this answer (and responses from the answerer)
neutral xxxmuitoprazer: conveys the right meaning,but no scientist/medical pro would frame it like this
13 hrs
  -> All references come from scientific sources, but then again, that doesn't mean my suggestion is the right one. Thanks again!
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