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16:08 May 21, 2002 |
Spanish to English translations [PRO] Medical / drugs - penicillin | |||||||
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| Selected response from: José Luis Villanueva-Senchuk (X) Argentina Local time: 10:30 | ||||||
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4 +2 | acylureidopenicillins |
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acylureidopenicillins Explanation: Suerte, JL -------------------------------------------------- Note added at 2002-05-21 16:34:56 (GMT) -------------------------------------------------- Good luck fighting the pseudomonas... \"Antipseudomonal penicillins Only the indanyl carbenicillin has an oral dose form. Other antipseudomonal penicillins are given IV/IM. Antipseudomonal penicillins include the carboxypenicillins (carbenicillin and ticarcillin), ***acylureidopenicillins (azlocillin and mezlocillin)***, and one piperazine penicillin derivative (piperacillin). With the exception of the indanyl derivative of carbenicillin, which is an oral dose form, all are for parenteral use (IM or IV). Except for carbencillin, the reason most of these drugs are used parenterally is that they are poorly absorbed orally rather than because they are destroyed by gastric acidity. All of these drugs are sensitive to beta-lactamase destruction. Piperacillin is more active than the others against Pseudomonas aeruginosa in vitro and has activity that corresponds to gentamicin, an aminoglycoside. Although carbenicillin and others in this group are active against many gram-positive organisms, they are generally less effective than penicillin G and ampicillin. There is not strong support for their use against infections caused by gram-positive bacteria. \" |
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