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1 sentence of 141 words with 2 doubts

English translation: sugerencias abajo

10:27 Aug 30, 2001
Spanish to English translations [PRO]
Medical
Spanish term or phrase: 1 sentence of 141 words with 2 doubts
Recientemente se ha propuesto un nuevo índice para cuantificar la RI partiendo de los valores basales de glucemia e insulinemia, el valor QUICKI (quantitative insulin sensitivity check index), expresado como 1/(log(FPI)+log(FPG)), que muestra una alta correlación con el índice de sensibilidad a la insulina derivado de la técnica del CLAMP, fundamentalmente para valorar pacientes obesos, pero tiene el inconveniente de ser un índice adimensional y de carecer de sentido fisiológico al situarse una suma de variables en el denominador con diferentes unidades de medida (dada la relación hiperbólica entre sensibilidad a la insulina y la FPI, la interacción entre ambas variables está definida matemáticamente por el producto de las mismas), y además no supone un avance sobre los valores de resistencia a la insulina estimados con el método HOMA, ya que el inverso de QUICKI es una transformación lineal del log(HOMA).

MY DRAFT (5 sentences)

A new index called the QUICKI value (Quantitative Insulin Sensitivity Check Index), expressed as 1/(Log(FPI)+Log(FPG)), has recently been proposed to quantify Insulin Resistance from basal glycemia and insulinemia values (42). It ((SHOWS A STRONG CORRELATION WITH/IS VERY SIMILAR TO)) the insulin sensitivity index derived from the clamp technique and is used fundamentally to evaluate obese patients. It has the drawback, however, of being an adimensional index and, furthermore, lacks physiological sense ((SINCE A SUM OF VARIABLES HAVING DIFFERENT MEASUREMENT UNITS ARE LOCATED IN THE DENOMINATOR/SINCE THE DENOMINATOR CONSISTS OF A SUM OF VARIABLES HAVING DIFFERENT MEASUREMENT UNITS)) (Note that given the hyperbolic relationship between insulin sensitivity and Fasting Plasma Insulin, the interaction between both variables is defined mathematically by their product). Finally, QUICKI does not represent an advance on the insulin resistance values estimated using the HOMA method, given that its inverse is a linear transformation of Log(HOMA).

Apart from the sheer length plus the admixture of notions, the two problems are those in CAPITALs. I'd appreciate any insight into the alternatives (the blatantly literal (unsatisfactory, to my mind) vs my interpretation).
Lia Fail (X)
Spain
Local time: 20:37
English translation:sugerencias abajo
Explanation:
Tus dudas, y las palabras que sugierio cambiar, van entre *...*, seguidos por mis sugerencias entre /.../
-------------------------------------
(Nota que en el caso del *the*// casi al final, sugiero cortarlo nada más.)
-------------------------------------

A new index called the QUICKI value (Quantitative Insulin Sensitivity Check Index), expressed as 1/(Log(FPI)+Log(FPG)), has recently been proposed to quantify Insulin Resistance *from*/using/ basal glycemia and insulinemia values (42). It *((SHOWS A STRONG CORRELATION WITH/IS VERY SIMILAR TO))*/shows a strong (HIGH) correlation with/ the insulin sensitivity index derived from the clamp technique and is used fundamentally to evaluate obese patients. It has the drawback, however, of being an adimensional index and, furthermore, *lacks physiological sense*/lacks a direct physiological interpretation/does not make sense physiologically/ *((SINCE A SUM OF VARIABLES HAVING DIFFERENT MEASUREMENT UNITS ARE LOCATED IN THE DENOMINATOR/SINCE THE DENOMINATOR CONSISTS OF A SUM OF VARIABLES HAVING DIFFERENT MEASUREMENT UNITS))*/since the denominator is a sum of variables with different units of measurement/ (Note that given the hyperbolic relationship between insulin sensitivity and Fasting Plasma Insulin, the interaction between *both*/these/ variables is defined mathematically by their product). Finally, QUICKI does not represent an *advance*/improvement/ on *the*// insulin resistance values estimated using the HOMA method, given that its inverse is a linear transformation of Log(HOMA).

Selected response from:

Margaret Schroeder
Mexico
Local time: 12:37
Grading comment
Thanks to both, but this provided additional help.
4 KudoZ points were awarded for this answer



Summary of answers provided
naQUICKI values demonstrate a high degree of correlation
Louise Ferguson
nasugerencias abajo
Margaret Schroeder


  

Answers


35 mins
QUICKI values demonstrate a high degree of correlation


Explanation:
This gives a better 'statistical flavor' than your own options in the first doubt (correlation always being a matter of 'degree').
The wording of the second option you propose for the second doubt seems fine to me.

Louise Ferguson
United Kingdom
Local time: 19:37
Login to enter a peer comment (or grade)

38 mins
sugerencias abajo


Explanation:
Tus dudas, y las palabras que sugierio cambiar, van entre *...*, seguidos por mis sugerencias entre /.../
-------------------------------------
(Nota que en el caso del *the*// casi al final, sugiero cortarlo nada más.)
-------------------------------------

A new index called the QUICKI value (Quantitative Insulin Sensitivity Check Index), expressed as 1/(Log(FPI)+Log(FPG)), has recently been proposed to quantify Insulin Resistance *from*/using/ basal glycemia and insulinemia values (42). It *((SHOWS A STRONG CORRELATION WITH/IS VERY SIMILAR TO))*/shows a strong (HIGH) correlation with/ the insulin sensitivity index derived from the clamp technique and is used fundamentally to evaluate obese patients. It has the drawback, however, of being an adimensional index and, furthermore, *lacks physiological sense*/lacks a direct physiological interpretation/does not make sense physiologically/ *((SINCE A SUM OF VARIABLES HAVING DIFFERENT MEASUREMENT UNITS ARE LOCATED IN THE DENOMINATOR/SINCE THE DENOMINATOR CONSISTS OF A SUM OF VARIABLES HAVING DIFFERENT MEASUREMENT UNITS))*/since the denominator is a sum of variables with different units of measurement/ (Note that given the hyperbolic relationship between insulin sensitivity and Fasting Plasma Insulin, the interaction between *both*/these/ variables is defined mathematically by their product). Finally, QUICKI does not represent an *advance*/improvement/ on *the*// insulin resistance values estimated using the HOMA method, given that its inverse is a linear transformation of Log(HOMA).



Margaret Schroeder
Mexico
Local time: 12:37
Native speaker of: Native in EnglishEnglish
PRO pts in pair: 1449
Grading comment
Thanks to both, but this provided additional help.
Login to enter a peer comment (or grade)



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