|Spanish to English translations [PRO]|
Medical - Medical (general)
|Spanish term or phrase: adenoma velloso verosimilmente malignizado|
|adenoma velloso verosimilmente malignizado|
I have noticed some of you are concerned about the number of questions I have posted. The limit is 15 in 24 hours for platinum. I went through the source text and made notes and I am now posting them all together as I did not have internet access earlier. Thanks for your understanding and input. Regards,
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Local time: 11:45
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malignant villous adenoma//malignant progression of the villous adenoma
Seguro que hay una manera de expresar mejor el término.
Estas son sólo pistas.
Buena suerte y saludos del Oso ¶:^)
Note added at 2005-08-11 21:52:08 (GMT)
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\"...Mortality/Morbidity: The immediate risks of adenomas include hemorrhage, obstruction with intussusception, and, possibly, torsion. However, the main concern is ***malignant progression of the villous adenoma***. Studies have defined the risk of progression of adenomas to adenocarcinoma.
* Precolonoscopy studies show the cumulative risk for carcinoma from polyps larger than 1 cm to be 4%, 14%, and 37% with 5, 10, and 20 years of follow-up, respectively. The risk for persons with carcinoma at sites other than the reference polyp is 4 times greater than that of the general population. The likelihood that an adenoma contains villous tissue, high-grade dysplasia, or invasive carcinoma is proportional to its size.
* Using complete colonoscopies, the National Polyp Study (NPS) prospectively followed 1418 patients diagnosed with 1 or more adenomas. An incidence reduction rate of 76-90% of colorectal cancers occurred, with only 10-24% of cancers that would be predicted from a reference population. This study found that the only independent predictive factors for progression from adenoma to adenocarcinoma were adenoma size and villous histology. The NPS study defined advanced polyps as larger than 1 cm or as those containing villous tissue or high-grade dysplasia.
* Overall, villous adenomas have a malignant risk of 15-25%. The risk of adenocarcinoma approaches 40% in villous adenomas larger than 4 cm in diameter. Patients with a rectosigmoid adenoma larger than 1 cm (or villous histology) had a 3.6-fold risk of developing adenocarcinoma compared to the general population. Villous adenomas of the ampulla of Vater contain carcinoma in 30-50% of cases, and carcinoma is found in 20-25% of duodenal villous adenomas. ...\"
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