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13:34 Oct 20, 2006 |
Spanish to English translations [PRO] Medical - Medical (general) / Research report for new drug | |||||||
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| Selected response from: Lia Fail (X) Spain Local time: 21:41 | ||||||
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was more than the proportion of doses between Explanation: Hi, Hope it clears some of the doubts. Suerte, Sonia |
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was greater than the amount found in doses betwee Explanation: la proporcional a la--that provided by literally -------------------------------------------------- Note added at 3 hrs (2006-10-20 16:48:16 GMT) -------------------------------------------------- -oops--I just notice the "n" missing . Doesn't proz have a spellchecker?? |
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was greater than the dose-proportional exposure for a dose range of Explanation: Thanks for draft, always very helpful:-) Draft: By contrast, in the 26 week duration oral toxicity study via orogastric tube in rats, the increase in exposure was greater than... 100 and 300 mg/Kg/day, and at doses of between 30 and 300 mg/Kg/day, the female rats were subject to higher exposure than the males. Second part (new sentence): y a dosificaciones de entre 30 y 300 mg/Kg/día, las ratas hembra tuvieron una exposición más alta que los machos. At doses of between 30 and 300 mg/Kg/day, furthermore, the exposure of the female rats was higher than that of the male rats. Alternative 1 for first part (literal): En cambio, en el estudio de toxicidad oral por sonda orogástrica de 26 semanas de duración realizado en ratas, el aumento en la exposición fue mayor que la proporcional a la dosificación entre 100 y 300 mg/Kg/día, In contrast, in the 26-week long orogastric-tube toxicity study in rats, the increase in exposure was greater than the proportional exposure to doses of between 100 and 300 mg/Kg/day. Alternative 2 (educated guess): En cambio, en el estudio de toxicidad oral por sonda orogástrica de 26 semanas de duración realizado en ratas, el aumento en la exposición fue mayor que la proporcional a la dosificación entre 100 y 300 mg/Kg/día, In contrast, in the 26-week long orogastric-tube toxicity study in rats, the increase in exposure was greater than the dose-proportional exposure for a dose range of 100 to 300 mg/Kg/day. References: [PDF] C:\Data\Lei's folder\Review reports\NDA-550\NDA-21042\SE5-S026\re ... File Format: PDF/Adobe Acrobat - View as HTML dose-proportional exposure in the effective dose ranges in JRA and RA patients. In fact,. clearance data from adult RA patients was 32% lower than that in ... www.fda.gov/cder/foi/esum/2004/21042se5-026,21052se5-019_Vi... - Similar pages Clinical Trial Results by Drug Names The Fuzeon 75mg bid dose had a slightly higher than dose-proportional exposure. Trough enfuvirtide concentrations for the Fuzeon 75mg and 100mg bid dose ... www.roche-trials.com/patient/trialresults/stur18.html - 46k - Cached - Similar pages Tolerability and steady-state pharmacokinetics of everolimus in ... These results indicate that up to 5 mg/day everolimus results in a dose-proportional exposure, and is adequately well tolerated in renal transplant ... cat.inist.fr/?aModele=afficheN&cpsidt=16189198 - Similar pages Antifungal efficacy of caspofungin(MK-0991) in experimental ... The CAS 1, CAS 3, and CAS 6 dose regimens demonstrated dose-proportional exposure and maintained drug levels in plasma above the MIC for the entire 24-h ... cat.inist.fr/?aModele=afficheN&cpsidt=13442170 - Similar pages [PDF] A PHASE I DOSE-ESCALATION AND PHARMACOKINETIC (PK) STUDY OF A ... File Format: PDF/Adobe Acrobat - View as HTML Preliminary PK analysis indicates that XL647 shows approximately dose-proportional exposure,. with a mean time to maximal concentration (t ... library.corporate-ir.net/library/12/120/120923/items/174686/XL647.pdf - Similar pages [PDF] A PHASE I DOSE-ESCALATION AND PHARMACOKINETIC (PK) STUDY OF A ... File Format: PDF/Adobe Acrobat - View as HTML XL647 shows approximately dose-proportional exposure, a mean time to maximal concentration (t. max. ) of. 6–9 hours, and an elimination half-life of ... www.exelixis.com/downloads/XL647-ASCO-Jun2006.pdf - Similar pages In the dose range of 0. 5-2. 0 mg/kg, acetylsalicylic acid does ... In the dose range of 0. 5-2. 0 mg/kg/day, ASA has a favorable effect on the ratio of prostacyclin to thromboxane A 2 in hypertensive pregnancies. cat.inist.fr/?aModele=afficheN&cpsidt=1666091 - Similar pages The nonclinical safety evaluation of the anticancer drug ATRAGEN ... Moderate to marked retinoid-associated hypervitaminosis A was observed in the 28-day rats studies in the dose range of 10 to 25 mg/kg/day. ... cat.inist.fr/?aModele=afficheN&cpsidt=1336704 - Similar pages [ More results from cat.inist.fr ] 787. Azocyclotin (Pesticide residues in food: 1989 evaluations ... The weight gain of the dams was reduced at 100 mg/kg/day but the response ... or the fetuses over the dose range of 30 to 300 mg/kg by dermal application. ... www.inchem.org/documents/jmpr/jmpmono/v89pr03.htm - 12k - Cached - Similar pages In the dose range of 0.5-2.0 mg/kg, acetylsalicylic acid does not ... CONCLUSION: In the dose range of 0.5-2.0 mg/kg/day, ASA has a favorable effect on the ratio of prostacyclin to thromboxane A2 in hypertensive pregnancies. ... www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubM... - Similar pages |
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