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células enteras que sobreexpresan al transportador de NE humana

English translation: whole cells that overexpress the human NE transporter

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GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
Spanish term or phrase:células enteras que sobreexpresan al transportador de NE humana
English translation:whole cells that overexpress the human NE transporter
Entered by: Adam Burman
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11:44 Oct 24, 2006
Spanish to English translations [PRO]
Medical - Medical (general) / Research report for new drug
Spanish term or phrase: células enteras que sobreexpresan al transportador de NE humana
En tejido cerebral de rata, desvenlafaxina inhibe la unión de 3H citalopram al transportador de 5-HT con una Ki de 20 nM, y la de [3H]nisoxetina al transportador de NE con un valor de Ki de 940 nM. DVS-233 compitió por [3H]nisoxetina, un inhibidor conocido de la recaptación de NE, unión que utiliza a células enteras que sobreexpresan al transportador de NE humana.

Draft:
In rat brain tissue, desvenlafaxine inhibits 3H citalopram binding to the 5-HT transporter with a Ki of 20 nM, and [3H]nisoxetine binding to the NE transporter with a Ki value of 940 nM. DVS-233 competed for the binding of [3H]nisoxetine, a known NE reuptake inhibitor which uses…

Many thanks
Adam Burman
United Kingdom
Local time: 10:06
whole cells that overexpress the human NE transporter
Explanation:
In rat brain tissue, desvenlafaxine inhibits 3H citalopram FROM binding to the 5-HT transporter with a Ki of 20 nM, and [3H]nisoxetine FROM binding to the NE transporter with a Ki ---- of 940 nM. DVS-233 competeS for ---- [3H]nisoxetine, a known NE reuptake inhibitor. THIS BINDING PROCESS uses…

whole cells that overexpress the human NE transporter.

I preferred a new sentence to avoid the which and that clause layering. Also, why the past with compitió? Is it a description of a process or of results?

I'm not to sure about this, so hopefully someone else can add something of their own.


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Note added at 3 hrs (2006-10-24 14:57:16 GMT)
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In reporting the results, it's normal to use past, although you should use your discretion, becaiuse sometimes a general truth is tossed in:-)
Selected response from:

xxxLia Fail
Spain
Local time: 11:06
Grading comment
Thanks Lia, I am grateful for your input on this and other questions.
4 KudoZ points were awarded for this answer

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Summary of answers provided
3 +2whole cells that overexpress the human NE transporterxxxLia Fail


Discussion entries: 1





  

Answers


20 mins   confidence: Answerer confidence 3/5Answerer confidence 3/5 peer agreement (net): +2
whole cells that overexpress the human NE transporter


Explanation:
In rat brain tissue, desvenlafaxine inhibits 3H citalopram FROM binding to the 5-HT transporter with a Ki of 20 nM, and [3H]nisoxetine FROM binding to the NE transporter with a Ki ---- of 940 nM. DVS-233 competeS for ---- [3H]nisoxetine, a known NE reuptake inhibitor. THIS BINDING PROCESS uses…

whole cells that overexpress the human NE transporter.

I preferred a new sentence to avoid the which and that clause layering. Also, why the past with compitió? Is it a description of a process or of results?

I'm not to sure about this, so hopefully someone else can add something of their own.


--------------------------------------------------
Note added at 3 hrs (2006-10-24 14:57:16 GMT)
--------------------------------------------------

In reporting the results, it's normal to use past, although you should use your discretion, becaiuse sometimes a general truth is tossed in:-)

xxxLia Fail
Spain
Local time: 11:06
Specializes in field
Native speaker of: Native in EnglishEnglish
PRO pts in category: 100
Grading comment
Thanks Lia, I am grateful for your input on this and other questions.

Peer comments on this answer (and responses from the answerer)
agree  liz askew: yes. See: [PDF] UK Strategy for Research and Development on Human and Animal ...File Format: PDF/Adobe Acrobat - View as HTML
55 mins

agree  Catriona Kirkwood: I agree
1 hr
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