Marie-Pierre GERARD - English to French translator. Translation services in Medical (general) - médical,médecine,pharmacie,pharmaceutique,laboratoire,notice, mode d\'emploi,scientifique,informatique,site web,article de presse,loisirs crétifs,travaux manuels,livres pour enfants medicine, pharmacology, biology, advertising, cosmetics, software, press release, book for children, arts and crafts, user manual, medical device, medical incident reports.

Working languages:

English to French

Marie-Pierre GERARD
5 years studying medicine

Local time: 12:53 CET (GMT+1)

Native in: French

Send message

Willingness
to Work Again
2 Positive entries

Profile

Contact

Freelancer,

Verified site user

Translation, Editing/proofreading, Project management

Specializes in:
Medical (general)	Medical: Cardiology
Medical: Health Care	Medical: Instruments
Medical: Pharmaceuticals

Questions answered: 63, Questions asked: 0 Easy / 2 PRO, PRO-level points: 105

Sample translations submitted: 1

English to French: Medical

Source text - English
The vascular endothelium of tumour tissue, which differs in several ways from that of normal tissues, is a potential target for selective anticancer therapy. By contrast with antiangiogenic agents, antivascular agents target the endothelial cells of existing tumour blood vessels, causing distortion or damage and consequently decreasing tumour blood flow. DMXAA (5,6-dimethylxanthenone-4-acetic acid), a low-molecular-weight drug, has a striking antivascular and in some cases curative effect in experimental tumours. Its action on vascular endothelial cells seems to involve a cascade of events leading to induction of tumour haemorrhagic necrosis. These events include both direct and indirect effects, the latter involving the release of further vasoactive agents, such as serotonin, tumour necrosis factor, other cytokines, and nitric oxide from host cells. Phase I clinical trials of DMXAA have been completed and the next challenge to face is how the antivascular effect of this drug should be exploited for the treatment of human cancer.

Translation - French
L'endothélium vasculaire du tissu tumoral, très différent en de nombreux points de celui des tissus normaux, est une cible potentielle pour une thérapie anti-cancéreuse sélective. Contrairement aux agents anti-angiogéniques, les agents anti-vasculaires ciblent les cellules endothéliales des vaisseaux sanguins tumoraux déjà existants, causant des déformations et des dommages et diminuant en conséquence le débit sanguin de la tumeur. Le DMXAA (acide 5,6-dimethylxanthenone-4-acétique), une substance à faible poids moléculaire, a un effet anti-vasculaire impressionnant sur les tumeurs expérimentales et parfois même un effet curatif. Son action sur les cellules endothéliales des vaisseaux sanguins semble induire, en cascade, une nécrose hémorragique de la tumeur. Cette action repose à la fois sur des effets directs et indirects : parmi ces derniers la libération d'agents vasoactifs supplémentaires, comme la sérotonine, le facteur de nécrose tumorale, d'autres cytokines et de l'oxyde nitrique venant des cellules hôtes. La Phase I des essais cliniques du DMXAA est terminée et le prochain défi sera de voir comment utiliser l'effet anti-vasculaire de cette substance dans le traitement du cancer chez l'homme.

mpgtraduction

Years of translation experience: 4. Registered at ProZ.com: Feb 2003.

N/A

English to French (Université de Paris-Sorbonne Nouvelle (Maîtrise))

SFT

Dreamweaver, Office 2003, Powerpoint, STAR Transit, Wordfast

CV/Resume (DOC)

Marie-Pierre GERARD endorses ProZ.com's Professional Guidelines.

About me

Translation in biology, medicine and pharmacology fields.
General translation of jobs related to advertising ( cosmetics, educational), press release, NGO reports, user manual (arts and crafts).

MA in English linguistics and translation (translation of a book: mention TB

Keywords: médical, médecine, pharmacie, pharmaceutique, laboratoire, notice, mode d\'emploi, scientifique, informatique, site web, article de presse, loisirs crétifs, travaux manuels, livres pour enfants medicine, pharmacology, biology, advertising, cosmetics, software, press release, book for children, arts and crafts, user manual, medical device, medical incident reports.

Profile last updated
Feb 24

More translators and interpreters: English to French More language pairs

Sign in to your ProZ.com account...

Or create a new account

Why did the menu change?

Where is the "My ProZ.com" menu?

I cannot find something


	X Sign in to your ProZ.com account... Username: Password: Forgot your password? Or create a new account


	X Why did the menu change? The updates to the menu were made to make the site easy and more intuitive for visitors. Obviously, like any change, this may take a few days to get used to. The dropdown menus have been divided into two-dimensional panels with similar items grouped together under headings. This eliminates scrolling for those with smaller screens, and also improves readability. More information on the changes... Where is the "My ProZ.com" menu? Mouseover your name at the top of the screen. Here you will find information about your account, your email settings, and more. The "My ProZ.com" menu was moved up here to simplify the main navigation, and to keep all of this type of information together. I cannot find something If you are having trouble finding something with the new menu, please submit a support request.